727419-35-4Relevant academic research and scientific papers
Synthesis of iridium complexes with new planar chiral chelating phosphinyl-imidazolylidene ligands and their application in asymmetric hydrogenation
Focken, Thilo,Raabe, Gerhard,Bolm, Carsten
, p. 1693 - 1706 (2004)
The synthesis of planar chiral phosphinoimidazolium salts such as (R p)-3-(4-diphenyl-phosphino[2.2]paracyclophan-12-ylmethyl)-1-(2, 6-diisopropylphenyl)imidazolium bromide (Rp)-11c starting from enantiopure 4,12-dibromo[2.2]paracyclophane (Rp)-6 is reported. After deprotonation of these salts and a subsequent reaction with [Ir(COD)Cl] 2, chelating iridium imidazolylidene complexes (Rp)-5a-c are obtained. These complexes catalyze the asymmetric hydrogenation of functionalized and simple alkenes with up to 89% ee.
