72744-22-0Relevant academic research and scientific papers
Rh(III)-catalyzed cyclization reaction of azoles with alkynes: Efficient synthesis of azole-fused-pyridines
Chen, Xuebing,Wu, Youzhi,Xu, Jinyi,Yao, Hequan,Lin, Aijun,Huang, Yue
, p. 9186 - 9189 (2015/09/07)
A Rh(III)-catalyzed cyclization of azoles with alkynes has been developed. A variety of azole-fused-pyridines were obtained in good to excellent yields and regioselectivity. Both the C5 and the C4 position of azoles were suitable for the reaction.
Synthesis of Heterocycle-fused Pyridine N-Oxides from Oximes and Diazo Compounds via RhIII-Catalyzed C-H Activation and Annulation
Sun, Peng,Wu, Youzhi,Yang, Tie,Wu, Xiaoming,Xu, Jinyi,Lin, Aijun,Yao, Hequan
supporting information, p. 2469 - 2473 (2015/08/18)
A RhIII-catalyzed tandem C-H activation and C-N bond formation reaction between oximes and diazo compounds for the synthesis of heterocycle-fused pyridine N-oxides has been developed. The reaction exhibits good functional group tolerance and regioselectivity. After simple transformation, the 1-substituted, 1,3-disubstituted, 1,4-disubstituted and 1,3,4-trisubstituted heterocycle-fused pyridines were all obtained in high efficiency. Moreover, this strategy has also been expanded to the synthesis of a key intermediate for the construction of one potential anti-HIV agent.
