72753-12-9Relevant academic research and scientific papers
An efficient synthesis of nitrogen heterocycles by Cp*Ir-catalyzed N-cycloalkylation of primary amines with diols
Fujita, Ken-ichi,Fujii, Takeshi,Komatsubara, Atsuo,Enoki, Youichiro,Yamaguchi, Ryohei
, p. 673 - 682 (2008/09/18)
A new efficient method for the N-cycloalkylation of primary amines with diols catalyzed by a Cp*Ir complex have been developed. A variety of five-, six-, and seven-membered cyclic amines are synthesized in good to excellent yields in environmentally benign and atom economical manner with the formation of only water as a coproduct. A large scale synthesis of N-benzylpiperidine and a two-step asymmetric synthesis of (S)-2-phenylpiperidine using (R)-1-phenylethylamine as a starting primary amine have been also achieved.
Efficient intramolecular hydroamination of unactivated alkenes catalysed by butyllithium
Ates, Ali,Quinet, Coralie
, p. 1623 - 1626 (2007/10/03)
In this communication, we wish to report some preliminary results demonstrating, for the first time, that intramolecular hydroamination of unactivated alkenes can be performed efficiently using small quantities of nBuLi as the pre-catalyst. Wiley-VCH Verl
