72758-39-5Relevant academic research and scientific papers
Inactivation of S-adenosyl-L-homocysteine hydrolase by amide and ester derivatives of adenosine-5'-carboxylic acid
Wnuk, Stanislaw F.,Liu, Siming,Yuan, Chong-Sheng,Borchardt, Ronald T.,Robins, Morris J.
, p. 4162 - 4166 (2007/10/03)
S-Adenosyl-L-homocysteine (AdoHcy) hydrolase has been shown to have (576') hydrolytic activity with vinyl (5') or homovinyl (6') halides derived from adenosine (Ado). This hydrolyric activity is independent of its 3'- oxidative activity. The vinyl (or hom
Modification of the 5' Position of Purine Nucleosides. 2. Synthesis and Some Cardiovascular Properties of Adenosine-5'-(N-substituted)carboxamides
Prasad, Raj Nandan,Bariana, Dilbagh S.,Fung, Anthony,Savic, Milica,Tietje, Karin,et al.
, p. 313 - 319 (2007/10/02)
We have shown previously that the esters of adenosine-5'-carboxylic acid (10) represent a new class of potent nontoxic coronary vasodilators.For example, the ethyl ester (12), which is active by an intraduodenal or intravenous route in dogs, causes a larg
