727651-32-3

Basic information

• Product Name: 1-(β-D-glucopyranosyl)-5-bromoindole
• Synonyms: 1-(β-D-glucopyranosyl)-5-bromoindole
• CAS NO: 727651-32-3
• Molecular Weight: 358.189
• Mol File: 727651-32-3.mol

Chemical Properties

• CAS DataBase Reference: 1-(β-D-glucopyranosyl)-5-bromoindole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(β-D-glucopyranosyl)-5-bromoindole(727651-32-3)
• EPA Substance Registry System: 1-(β-D-glucopyranosyl)-5-bromoindole(727651-32-3)

Safety Data

• Hazardous Substances Data: 727651-32-3(Hazardous Substances Data)

Upstream product

• 22190-38-1 5-bromo-N-acetylindoline 

Downstream Products

• 727651-36-7 1-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-5-bromoindoline-2,3-dione 
• 727651-34-5 1-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-5-bromoindole 

Relevant articles and documents

Synthesis and antiproliferative activities of diversely substituted glycosyl-isoindigo derivatives

In the course of structure-activity relationship studies, diversely substituted 1-(β-D-glucopyranosyl)-isoindigo derivatives were prepared from commercially available indolines. Their antiproliferative activities were evaluated toward a panel of human solid cancer cell lines (PC 3, DLD-1, MCF-7, M4Beu, A549, PA 1), a murine cell line (L929) and a human fibroblast primary culture to get an insight into the substitution pattern required for the best biological potencies.

Synthesis of glycosyl-isoindigo derivatives

The synthesis of 1-(β-D-glucopyranosyl)-isoindigo from commercially available indoline is described. The synthetic pathway used allowed the substitution of the aromatic moiety by either electron donor or acceptor substituents.