72772-94-2

Basic information

• Product Name: 2-methyl-3-(phenylsulfonyl)benzofuran
• Synonyms: 2-methyl-3-(phenylsulfonyl)benzofuran
• CAS NO: 72772-94-2
• Molecular Weight: 272.324
• Mol File: 72772-94-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-methyl-3-(phenylsulfonyl)benzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-3-(phenylsulfonyl)benzofuran(72772-94-2)
• EPA Substance Registry System: 2-methyl-3-(phenylsulfonyl)benzofuran(72772-94-2)

Safety Data

• Hazardous Substances Data: 72772-94-2(Hazardous Substances Data)

Upstream product

• 533-58-4 2-Iodophenol 
• 220961-10-4 ((2-bromo-2-propenyl)sulfonyl)benzene 
• 873-55-2 sodium benzenesulfonate 
• 15068-08-3 o-chloromethylphenyl acetate 
• 1309773-28-1 C₁₅H₁₄O₄S 

Relevant articles and documents

Regioselective synthesis of arylsulfonyl heterocycles from bromoallyl sulfonesviaintramolecular Heck coupling reaction

Indoles, benzofurans and benzosultams endowed with arylsulfonyl groups were prepared in two steps from 2-bromoallyl sulfones.ortho-Halosulfonamides andortho-iodophenol reacted with 2-bromoallyl sulfones in the presence of cesium carbonate to furnish products resulting from a formal vinylic substitution reaction. Palladium-catalyzed intramolecular Heck reaction of these adducts furnished sulfonylated indoles, benzosultams and benzofurans. Isomerization of the double bond participating in the Heck reaction under basic conditions led to the formation of two isomeric products in two cases. Conditions for selectively accessing each of the regioisomeric indoles were developed.