727720-44-7Relevant academic research and scientific papers
Nucleophilic attack of 2-sulfinyl acrylates: A mild and general approach to sulfenic acid anions
Singh, Suneel P.,O'Donnell, Jennifer S.,Schwan, Adrian L.
supporting information; experimental part, p. 1712 - 1717 (2010/07/04)
An increasing number of reactions of sulfenic acid anions are being demonstrated in the literature. As such, mild, general and reliable means for the generation of sulfenates are due. In the current paper, an addition/elimination of 2-sulfinyl acrylates using various nucleophiles is demonstrated and evaluated as a protocol for alkane- and arenesulfenate generation. Cyclohexanethiolate, methoxide and n-butyllithum each exhibit some merit for the reaction, and the thiolate is established as a mild, selective and effective reagent to release sulfenates from 2-sulfinyl acrylates. The stereospecificity of the addition/elimination of each nucleophile is recognized, and an explanation for the specificity is offered for thiolate and methoxide.
Facile synthetic method for the preparation of dithioacetals by the double conjugate addition of acetylenes bearing electronwithdrawing groups with thiols
Kuroda, Hirofumi,Tomita, Ikuyoshi,Endo, Takeshi
, p. 1539 - 1543 (2007/10/03)
β, β-Bis(alkylmercapto)propionates were obtained by the reaction of methyl propiolates with 2 equiv. of mercaptanes in the presence of tri-n-butylphosphine in high yield. The corresponding dithioacetals could be also obtained by the conjugate addition of mercaptanes toward methyl β-alkylmercaptoenoates, in which, tri-n-butylphosphine also catalyzed the addition of thiols.
