727985-90-2Relevant academic research and scientific papers
Insulin-releasing activity of a series of phenylalanine derivatives
Tang, Lei,Yu, Juanhong,Wu, Haoshu,Fan, Houxing,Yang, Yushe,Ji, Ruyun
, p. 1997 - 2003 (2008/12/22)
A series of phenylalanine derivatives were synthesized and their biological activities were evaluated. Compounds (S)-3 and (R)-3 exhibited more potent insulin-releasing activity than that of nateglinide, compound (S)-3 also showed insulin-sensitizing activity in vitro. Both compounds were tested for hypoglycemia effect in vivo.
ALANINES COMPOUNDS, METHOD OF PREPARING THEM AND THEIR USE
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Page/Page column 13, (2008/06/13)
The present invention provides alanine compounds of formula (I) or their salts: In the formula (I), the configuration of α ― Carbon atom of alanine is R or S; R1 is hydrogen, unsubstituted or substituted C1-6 alkyl, unsubstituted or
