727993-74-0

Usage

Uses

Used in Pharmaceutical Industry:
Tert-butyl-5-Methoxy-2,3-dihydropyrrolo[2,3-c-]pyridine-1-carboxylate is used as a key intermediate in the synthesis of pharmaceuticals for various therapeutic applications. Its unique structure and functional groups make it a versatile component in the development of new drugs with improved efficacy and safety profiles.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, Tert-butyl-5-Methoxy-2,3-dihydropyrrolo[2,3-c-]pyridine-1-carboxylate serves as a valuable building block for the design and synthesis of biologically active molecules. Its presence in these molecules can modulate their pharmacological properties, leading to the discovery of novel therapeutic agents with potential applications in treating various diseases and conditions.
Used in Drug Discovery:
Tert-butyl-5-Methoxy-2,3-dihydropyrrolo[2,3-c-]pyridine-1-carboxylate is utilized in drug discovery processes to explore its potential as a precursor for the development of new pharmaceutical agents. Its unique structural features and reactivity make it an attractive candidate for the creation of innovative drug molecules with enhanced therapeutic properties.

Upstream product

• 727993-73-9 2-{5-[(tert-butoxycarbonyl)amino]-2-methoxypyridin-4-yl}ethyl methanesulfonate 
• 6628-77-9 6-methoxy-pyridin-3-ylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 183741-80-2 tert-butyl N-(6-methoxypyridin-3-yl)carbamate 
• 727993-72-8 tert-butyl [4-(2-hydroxyethyl)-6-methoxypyridin-3-yl]carbamate 

Downstream Products

• 412030-10-5 5-methoxy-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine 
• 1403898-96-3 6-benzyl-1,2,3,6-tetrahydro-pyrrolo[2,3-c]pyridin-5-one hydrochloride 
• 1403898-95-2 6-benzyl-5-oxo-2,3,5,6-tetrahydro-pyrrolo[2,3-c]pyridine-1-carboxylic acid tert-butyl ester 
• 727993-81-9 N-(4-methoxy-9-oxo-6-phenyl-1,2,8,9-tetrahydro-5,7,9a-triaza-benzo[cd]azulen-8-yl)-nicotinamide 
• 727993-79-5 8-azido-4-methoxy-6-phenyl-1,2-dihydro-8H-5,7,9a-triaza-benzo [cd] azulen-9-one 
• 727993-80-8 8-Amino-4-methoxy-6-phenyl-1,2-dihydro-8H-5,7,9a-triaza-benzo[cd]azulen-9-one 
• 727993-78-4 4-methoxy-6-phenyl-1,2-dihydro-8H 5,7,9a-triaza-benzo[cd]azulen-9-one 
• 727993-77-3 5-methoxy-2,3-dihydro-1H-pyrrolo[2,3-c]pyridin-7-yl(phenyl)methanone 
• 727993-76-2 5-methoxy-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile 

Relevant academic research and scientific papers

Preparation of azaindolines and benzoyl substituted azaindolines: Precursors of triazabenzo[cd]azulen-9-one PDE4 inhibitors

The syntheses of various substituted azaindolines are described. Azaindolines were identified as potential key intermediates towards new PDE4 inhibitors.

Azabenzodiazepines as pde4 inhibitors

Compounds of formula (I): characterized in that:R1 represents a group selected from hydrogen atom, methyl, methoxy, hydroxy, amino, dimethylamino, acetamido, pyrrolidin-1-yl, and hydroxymethyl;R2 represent a group selected from phenyl, pyridyl, pyrimidyl, quinolyl, isoquinolyl, indolyl, pyrolyl, [1,2,3]-triazolyl, benzo[c]isoxazolyl, thienyl, pyrazolyl, isothiazolyl, imidazolyl, benzofuranyl, pyrazolo[5,1-c][1,2,4]triazyl each of these groups being optionally substituted from 1 to 3 groups, identical or different independently of each other, selected from halogen, trifluoromethyl, (C1-C4)alkyl, (C1-C4)alkoxy, hydroxy, amino, acetamido, tert-butyloxycarbonylamino, cycloalkylcarbonylamino, sulfonamide, nitro, acetylmethoxy, cyclopentyloxy; optionally, their optical isomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and their use as active ingredient in pharmaceutical composition useful for treating diseases involving therapy by inhibition of PDE4.