728-15-4

Basic information

• Product Name: Acetic acid, (diphenylhydrazono)-
• CAS NO: 728-15-4
• Molecular Formula: C14H12N2O2
• Molecular Weight: 240.261
• Mol File: 728-15-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetic acid, (diphenylhydrazono)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (diphenylhydrazono)-(728-15-4)
• EPA Substance Registry System: Acetic acid, (diphenylhydrazono)-(728-15-4)

Safety Data

• Hazardous Substances Data: 728-15-4(Hazardous Substances Data)

Upstream product

• 530-47-2 N,N-diphenylhydrazine hydrochloride 
• 298-12-4 Glyoxilic acid 

Downstream Products

• 220587-72-4 1,6-anhydro-2-O-benzoyl-4-deoxy-3-O-(diphenylhydrazono)acetyl-4-iodo-β-D-glucopyranose 
• 220587-71-3 3-O-benzyl-6-bromo-6-deoxy-5-O-(diphenylhydrazono)acetyl-1,2-O-isopropylidene-α-D-glucofuranose 
• 220587-63-3 phenyl 2-O-(diphenylhydrazono)acetyl-1-seleno-3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-α-L-arabinofuranoside 
• 220587-61-1 phenyl 2-O-(diphenylhydrazono)acetyl-1-seleno-3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranoside 
• 220587-65-5 phenyl 3,5,6-tri-O-benzyl-2-O-(diphenylhydrazono)-acetyl-1-seleno-β-D-glucofuranoside 
• 220587-95-1 (2R,3S,4R,5R)-2-[(R)-2-(tert-Butyl-diphenyl-silanyloxy)-1-(N',N'-diphenyl-hydrazino)-ethyl]-5-((R)-1,2-dimethoxy-ethyl)-4-methoxy-tetrahydro-furan-3-ol 
• 220587-94-0 3,6-anhydro-1-O-<(1,1-dimethylethyl)diphenylsilyl>-2-deoxy-2-(2,2-diphenylhydrazino)-5,7,8-tri-O-methyl-D-erythro-L-ido-octitol 
• 220587-79-1 3,6-anhydro-2-deoxy-2-(2,2-diphenylhydrazino)-5,7,8-tri-O-methyl-D-erythro-L-ido-octono-1,4-lactone 
• 220587-80-4 3,6-anhydro-2-deoxy-2-(2,2-diphenylhydrazino)-5,7,8-tri-O-methyl-D-erythro-L-gulo-octono-1,4-lactone 

Relevant articles and documents

Preparation of α-(2,2-diphenylhydrazino)lactones and related compounds by radical cyclization: Use of glyoxylic acid hydrazone derivatives

Glyoxylic acid diphenylhydrazone (2a) and the corresponding O-benzyloxime (2b) are easily esterified in high yield by β-bromo alcohols. The resulting esters undergo radical cyclization to α-(2,2-diphenylhydrazino)- or α-[(phenylmethoxy)amino]lactones on treatment with tributyltin hydride. Esters for radical cyclization were also made using a β-(phenylseleno) alcohol and an enol ether. Several derivatives of glyoxylic acid were evaluated, but none was as effective as 2a or 2b. The imine 28 was prepared by an indirect route; it undergoes radical cyclization with displacement of the nitrogen substituent (28 → 30) so that an α-amino lactone can be generated by acid hydrolysis of the cyclization product.