728019-53-2Relevant academic research and scientific papers
TETRAHYDROISOQUINOLINE COMPOUNDS AS NRF2 ACTIVATORS
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Paragraph 00187, (2021/10/30)
The present invention relates to compounds that are Nrf2 activators. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with Nrf2 activation.
PYRROLOPYRIDAZINE DERIVATIVES
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Page 249, (2008/06/13)
The invention relates to compound of the formula (I) or its salt, in which R1, R2, R3 and R4 are as defined in the description, their use of as medicament, the process for their preparation and use for the treatment of PDE-IV or TNF-α mediated diseases.
