728023-77-6Relevant academic research and scientific papers
An efficient synthesis of quinazoline derivatives with the aid of low-valent titanium reagent
Shi, Daqing,Shi, Chunling,Wang, Juxian,Rong, Liangce,Zhuang, Qiya,Wang, Xiangshan
, p. 173 - 183 (2007/10/03)
Quinazolin-4(3H)-ones, 1,2-dihydroquinazolin-4(3H)-ones, 3,4-dihydroquinazolines, imidazo[1,2-c]-quinazolines and 5,6-dihydroimidazo[1,2- c]quinazolines were synthesized by the novel reductive reaction of nitro group, N-H bond and ortho-ester, aldehydes o
Synthesis of quinazolines and imidazo[1,2-c]quinazolines with the aid of a low-valent titanium reagent
Shi, Daqing,Wang, Juxian,Shi, Chunling,Rong, Liangce,Zhuang, Qiya,Hu, Hongwen
, p. 1098 - 1100 (2007/10/03)
A short and facile synthesis of a series of quinazolines and imidazo[1,2-c]quinazolines was accomplished in good yields via the novel reductive cyclization of 2-nitrobenzyl amines or 2-(2-nitrophenyl)imidazoles with ortho-ester, aldehydes or ketones promoted by TiCl4/Zn system. The structures were established by spectroscopic data and confirmed by X-ray analysis.
