72827-18-0Relevant academic research and scientific papers
Synthesis of N-substituted indole derivatives via PIFA-mediated intramolecular cyclization
Du, Yunfei,Liu, Renhe,Linn, Gregory,Zhao, Kang
, p. 5919 - 5922 (2007/10/03)
(Chemical Equation Presented) A variety of N-arylated and N-alkylated indole derivatives were synthesized by way of a phenyliodine bis(trifluoroacetate) (PIFA)-mediated intramolecular cyclization. This novel method allows for the construction of an indole skeleton by joining the N-atom on the side chain to the benzene ring at the last synthetic step. Other novel pyrrole-fused aromatic compounds can also be achieved by this method.
