72842-05-8 Usage
General Description
CYTIDINE 5'-DIPHOSPHOETHANOLAMINE SODIUM SALT is a chemical compound that consists of cytidine, a nucleoside, and a diphosphoethanolamine group, which is attached to the cytidine molecule through a phosphate bridge. It is in the form of a sodium salt. CYTIDINE 5'-DIPHOSPHOETHANOLAMINE SODIUM SALT plays a crucial role in the biosynthesis of phosphatidylethanolamine, a major component of cell membranes. It is also involved in the regulation of cell growth and differentiation. Additionally, it is an essential precursor for the synthesis of phospholipids, which are important for maintaining the structure and function of cell membranes. Moreover, it has potential therapeutic applications in the treatment of various diseases, including cancer and liver disorders, due to its role in cell membrane function and lipid metabolism.
Check Digit Verification of cas no
The CAS Registry Mumber 72842-05-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,8,4 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 72842-05:
(7*7)+(6*2)+(5*8)+(4*4)+(3*2)+(2*0)+(1*5)=128
128 % 10 = 8
So 72842-05-8 is a valid CAS Registry Number.
72842-05-8Relevant articles and documents
CDP-Ethanolamine and CDP-Choline: One-pot synthesis and 31P NMR study
Ghezal, Salma,Thomasson, Maggie S.,Lefebvre-Tournier, Isabelle,Périgaud, Christian,Macnaughtan, Megan A.,Roy, Béatrice
, p. 5306 - 5310 (2014)
Herein we report a one-pot multi-step synthesis of the cofactors CDP-Ethanolamine and CDP-Choline starting from cytidine 5′-monophosphate and using commercially available and/or easily prepared reagents. While studying the 31P NMR spectrum of CDP-Ethanolamine, an unexpected characteristic for a pyrophosphate diester was observed as it showed a singlet or two doublets depending upon the pH. Therefore, further NMR studies were undertaken to investigate the pH dependence of the peak splitting pattern and measure the acid dissociation constants of the compounds.
