72863-84-4

Usage

InChI:InChI=1/C6H2Cl5N/c7-2-1-3(8)6(11)12-4(2)5(9)10/h1,5H

Upstream product

• 72863-83-3 3,5,6-trichloro-4-hydrazino-2-trichloromethylpyridine 
• 120-94-5 1-Methylpyrrolidine 
• 2402-79-1 2,3,5,6-tetrachloropyridine 

Relevant academic research and scientific papers

Preparation of substituted (dichloromethyl)pyridines

2- and 4-(Dichloromethyl)pyridines containing electron withdrawing substituents on the ring are prepared by the reaction of the corresponding 2- or 4-halopyridines with excess chloroform in the presence of a strong base in a medium containing a dipolar aprotic solvent or a phase transfer catalyst. 3-Chloro-5-(trifluoromethyl)-2-(dichloromethyl)pyridine, for example, is prepared by the reaction of 2,3-dichloro-5-(trifluoromethyl)pyridine with chloroform in the presence of sodium hydroxide and N-methylpyrrolidone. Substituted 2-(dichloromethyl)pyridines are useful as agricultural pesticides and as intermediates for the preparation of agricultural pesticides.

Method for preparing dichloromethyl pyridines

Dichloromethylpyridine derivatives are prepared from hydrazino adducts of trichloromethylpyridine compounds by reacting said adducts with an aqueous alkaline solution in the presence of a refluxing carrier medium.