72916-49-5Relevant articles and documents
Synthesis, molecular modeling study, preliminary antibacterial, and antitumor evaluation of N-substituted naphthalimides and their structural analogues
El-Azab, Adel S.,Alanazi, Amer M.,Abdel-Aziz, Naglaa I.,Al-Suwaidan, Ibrahim A.,El-Sayed, Magda A. A.,El-Sherbeny, Magda A.,Abdel-Aziz, Alaa A.-M.
, p. 2360 - 2375 (2013/07/26)
Carboxylic acid imides 1-26 have been synthesized and screened for their antibacterial against gram-positive and gram-negative organisms and their antitumor activity against 60 tumor cell lines taken from nine different organs. Compounds 12, 14, and 16 we
N-SUBSTITUTED ISONAPHTHALIMIDES. FORMATION AND REACTION WITH AMINES
Ganin, E. V.,Makarov, V. F.,Nikitin, V. I.
, p. 2209 - 2215 (2007/10/02)
N-Substituted isonaphthalimides and N-substituted naphthalimides, as considered previously, are formed in the reaction of 1,8-naphthaloyl chloride with primary amines.The reaction of N-substituted isonaphthalimides with sterically unhindered amines leads to the N,N'-substituted diamides of 1,8-naphthalenedicarboxylic acid.In the case of sterically hindered amines it results in isomerization to the N-substituted naphthalimides.The thermolysis of the N,N'-substituted diamides of 1,8-naphthalenedicarboxylic acid leads to amines and N-substituted naphthalimides.
