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5-[(4-Chlorophenyl)hydrazono]pyrimidine-2,4,6(1H,3H)-trione is a complex organic compound with the molecular formula C10H6ClN5O3. It is a derivative of pyrimidine, a heterocyclic aromatic organic compound consisting of a six-membered ring, with four nitrogen atoms and two carbon atoms. The compound features a 4-chlorophenylhydrazono group attached to the 5-position of the pyrimidine ring, which introduces a chlorine atom to the phenyl ring. This chemical structure endows the molecule with unique properties, making it potentially useful in various chemical and pharmaceutical applications, such as the synthesis of new compounds or as an intermediate in the production of drugs. Its specific reactivity, stability, and potential applications would depend on further investigation into its chemical behavior and interactions with other substances.

7293-30-3

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7293-30-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7293-30-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,9 and 3 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7293-30:
(6*7)+(5*2)+(4*9)+(3*3)+(2*3)+(1*0)=103
103 % 10 = 3
So 7293-30-3 is a valid CAS Registry Number.

7293-30-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,4,5,6(1H,3H)-Pyrimidinetetrone, 5-[(4-chlorophenyl)hydrazone] (en)

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7293-30-3 SDS

7293-30-3Downstream Products

7293-30-3Relevant academic research and scientific papers

DNA and BSA binding, anticancer and antimicrobial properties of Co(II), Co(II/III), Cu(II) and Ag(i) complexes of arylhydrazones of barbituric acid

Palmucci, Jessica,Mahmudov, Kamran T.,Guedes Da Silva, M. Fátima C.,Marchetti, Fabio,Pettinari, Claudio,Petrelli, Dezemona,Vitali, Luca A.,Quassinti, Luana,Bramucci, Massimo,Lupidi, Giulio,Pombeiro, Armando J. L.

, p. 4237 - 4249 (2016)

Two new cocrystalline compounds, (Hen)(H2L2)·2/3H2O (2) and (Him)(H3L3)·2H2O (8), were prepared by the reaction of 5-(2-(4-chlorophenyl)hydrazono)pyrimidine-2,4,6(1H,3H,5H)-trione (H3

Synthesis, activity evaluation, and docking analysis of barbituric acid aryl hydrazone derivatives as RSK2 inhibitors

Xue, Mengzhu,Xu, Minghao,Lu, Weiqiang,Huang, Jin,Li, Honglin,Xu, Yufang,Liu, Xiaofeng,Zhao, Zhenjiang

, p. 747 - 752 (2013/07/26)

The 90 kDa ribosomal S6 kinases (RSKs), especially RSK2, have attracted attention for the development of new anticancer agents. Through structural optimization of the hit compound 1 from our previous study, a series of barbituric acid aryl hydrazone analogues were designed and synthesized as potential RSK2 inhibitors. The most potent one, compound 9, showed a higher activity against RSK2 with an IC50 value of 1.95 μM. To analyze and elucidate their structure-activity relationship, the homology model of RSK2 N-terminal kinase domain was built and molecular docking simulations were performed, which provide helpful clues to design new inhibitors with desired activities.

Preparation and Hydrogen Bonding Studies of Phenylhydrazone Derivatives of Alloxan: Crystal and Molecular Structure of Pyrimidine-2(1H),4(3H),5,6-tetraone-5-(2-Nitrophenyl)hydrazone

Beaton, Haydn G.,Willey, Gerald R.,Drew, Michael G. B.

, p. 469 - 472 (2007/10/02)

Eight phenylhydrazone derivatives of pyrimidine-2(1H),4(3H),5,6-tetraone, or 5-oxobarbituric acid (alloxan), are described.Spectroscopic pyrimidine (1H n.m.r., i.r.) data indicate the presence of extensive hydrogen bonding which, as shown by X-ray crystal

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