72962-53-9 Usage
General Description
24-methyl-23-dehydrocholesterol is a chemical compound that is a derivative of cholesterol and plays a crucial role in the synthesis of vitamin D in the skin. It is also known as lanosterol and is a precursor molecule in the biosynthesis of both cholesterol and vitamin D. In addition to its role in vitamin D synthesis, 24-methyl-23-dehydrocholesterol has been investigated for potential medical applications, including its potential as a therapeutic target in cardiovascular diseases. 24-methyl-23-dehydrocholesterol is primarily found in animal sources and is involved in the regulation of lipid metabolism and cholesterol synthesis within the body.
Check Digit Verification of cas no
The CAS Registry Mumber 72962-53-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,9,6 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 72962-53:
(7*7)+(6*2)+(5*9)+(4*6)+(3*2)+(2*5)+(1*3)=149
149 % 10 = 9
So 72962-53-9 is a valid CAS Registry Number.
InChI:InChI=1/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7,9,18,20,22-26,29H,8,10-17H2,1-6H3/b19-7-/t20-,22+,23+,24-,25+,26+,27+,28-/m1/s1
72962-53-9Relevant academic research and scientific papers
Structural and Stereochemical Aspects of Base-Catalyzed Double Bond Isomerization of Sterols with Unsaturated Side Chains
Li, Hui-ting,Djerassi, Carl
, p. 4298 - 4303 (2007/10/02)
A careful analysis of the N-lithioethylenediamine-catalyzed isomerization of 22-, 23-, and 24-methylenecholesterol demonstrated the existence of subtle factors which are responsible for the kinetically and thermodynamically preferred products.In general, the results can be related to the anticipated energy preferences of the intermediate carbanions.Through the use of 1H and 13C NMR spectroscopy the configuration of the various double bond isomers could be established.Since all major products are readily separated by HPLC, such base-catalyzed isomerization offers a convenient synthetic route to a variety of stereochemically pure sterol olefins, which either have been found in the marine environment or may be detected in the future.
