7299-50-5Relevant academic research and scientific papers
Chemoselective C-H bond activation: Ligand and solvent free iron-catalyzed oxidative C-C cross-coupling of tertiary amines with terminal alkynes. Reaction scope and mechanism
Volla, Chandra M. Rao,Vogel, Pierre
supporting information; experimental part, p. 1701 - 1704 (2009/09/06)
FeCI2 catalyzes the oxidative C-C cross-coupling of tertiary amines with terminal alkynes Into propargylamlnes using (t-BuO)2 as oxidant. The reaction can be applied to aromatic and aliphatic amines and alkynes without solvent. High chemoselectlvlty for amlnomethyl groups Is due to a steric factor.
