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Phentolamine hydrochloride is an adrenergic blocking agent, which is a synthetic compound with antihypertensive properties. It functions by blocking the action of certain neurotransmitters, specifically norepinephrine, and is commonly used in the treatment of pheochromocytoma, a rare tumor of the adrenal gland.

73-05-2

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73-05-2 Usage

Uses

Used in Pharmaceutical Industry:
Phentolamine hydrochloride is used as an antihypertensive agent for the treatment of pheochromocytoma, a rare tumor of the adrenal gland. It helps to control high blood pressure and alleviate symptoms associated with this condition.
Used in Anesthesia:
Phentolamine hydrochloride is used as a local anesthetic, providing pain relief during minor surgical procedures or other medical interventions. Its adrenergic blocking properties contribute to its effectiveness in this application.
Used in Cardiology:
Phentolamine hydrochloride is used as an inhibitor of DRG IA/Kv4.2 current, which plays a role in the regulation of cardiac ion channels. This application can help in the management of certain cardiac conditions by modulating the electrical activity of the heart.

Biochem/physiol Actions

α-adrenoceptor antagonist; peripheral vasodilator.

Check Digit Verification of cas no

The CAS Registry Mumber 73-05-2 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 73-05:
(4*7)+(3*3)+(2*0)+(1*5)=42
42 % 10 = 2
So 73-05-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H19N3O.ClH/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H

73-05-2 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
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  • Sigma

  • (P7547)  Phentolaminehydrochloride  ≥98% (TLC), powder

  • 73-05-2

  • P7547-100MG

  • 907.92CNY

  • Detail
  • Sigma

  • (P7547)  Phentolaminehydrochloride  ≥98% (TLC), powder

  • 73-05-2

  • P7547-500MG

  • 3,504.15CNY

  • Detail
  • USP

  • (1529005)  Phentolaminehydrochloride  United States Pharmacopeia (USP) Reference Standard

  • 73-05-2

  • 1529005-300MG

  • 4,662.45CNY

  • Detail

73-05-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol,hydrochloride

1.2 Other means of identification

Product number -
Other names Prestwick_386

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:73-05-2 SDS

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