73-09-6 Usage
Originator
Elkapin,Goedecke,W. Germany,1977
Manufacturing Process
To a stirred solution of 20 g (0.1 mol) 2-carbethoxymethylene-3-methyl-4-
thiazolidinone in 120 ml chloroform is added, dropwise, a solution of 5 ml (0.1
mol) bromine in 20 ml chloroform. The solvent is removed by distillation and
the residue crystallized from methanol to yield 18 g (65%) of 2-
carbethoxymethylen-3-methyl-5-bromo-4-thiazolidinone, MP 76°C.To a solution of 28 g (0.1 mol) 2-carbethoxymethylene-3-methyl-5-bromo-4-
thiazolidinone prepared as described in 200 ml benzene is added (0.2 mol)
piperidine and the mixture is allowed to stand for 3 hours at 25°C. The
resulting suspension is filtered to remove the precipitated piperidine
hydrobromide and the filtrate is evaporated to dryness. The residue is taken
up in ether, filtered and the filtrate saturated with dry hydrogen chloride to
yield the hydrochloride salt of 2-carbethoxymethylene-3-methyl-5-piperidino-
4-thiazolidinone, MP 158°C to 159°C.
Therapeutic Function
Diuretic
Check Digit Verification of cas no
The CAS Registry Mumber 73-09-6 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 3 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 73-09:
(4*7)+(3*3)+(2*0)+(1*9)=46
46 % 10 = 6
So 73-09-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H20N2O3S/c1-3-18-11(16)9-10-14(2)12(17)13(19-10)15-7-5-4-6-8-15/h9,13H,3-8H2,1-2H3/b10-9+
73-09-6Relevant articles and documents
Combination of two active substances
-
, (2008/06/13)
The invention concerns the use of a compound with diuretic properties and of a magnesium supplementation in the form of magnesium monoaspartate hydrochloride, magnesium oxide, magnesium hydroxide or magnesium carbonate, and optionally of a potassium supplementation, and pharmaceutical preparations comprising a compound with diuretic properties and a magnesium supplementation in the form of magnesium monoasparate hydrochloride, magnesium oxide, magnesium hydroxide, or magnesium carbonate and optionally a potassium supplementation.