73029-86-4

Usage

Uses

Used in Organic Synthesis:
2,3-Quinoxalinedione, 1,4-dihydro-, dihydrazone is used as a reagent for the derivatization and determination of carbonyl compounds. Its dihydrazone form allows for the creation of novel organic compounds, making it a valuable tool in the synthesis of various chemical entities.
Used in Pharmaceutical Applications:
Due to its unique molecular structure and reactivity, 2,3-Quinoxalinedione, 1,4-dihydro-, dihydrazone has potential applications in the development of pharmaceuticals. It can be utilized in the synthesis of new drug candidates or as a component in drug delivery systems, contributing to advancements in medicine.
Used in Agricultural Products:
2,3-Quinoxalinedione, 1,4-dihydro-, dihydrazone may also find use in the agricultural industry, where it could be employed in the synthesis of agrochemicals or as a component in the development of new pesticides or herbicides.
Used in Materials Science:
2,3-Quinoxalinedione, 1,4-dihydro-, dihydrazone's versatile reactivity and molecular structure make it a candidate for use in materials science, where it could be incorporated into the development of new materials with unique properties, such as advanced polymers or composites.
It is important to handle 2,3-Quinoxalinedione, 1,4-dihydro-, dihydrazone with care, as it may pose health hazards if not properly managed and stored.

Upstream product

• 1199-03-7 1,4-dihydro-quinoxaline-2,3-dithione 
• 15804-19-0 quinoxaline-2,3-dione 
• 95-54-5 1,2-diamino-benzene 
• 15804-19-0 2,3-dihydroxyquinoxaline 
• 2213-63-0 2,3-dichloroquinoxaline 

Downstream Products

• 75380-47-1 2,4-dihydro-5-methyl-2-phenyl-3H-pyrazole-3,4-dione 4-bis(quinoxaline-2,3-diylhydrazone) 
• 1361954-69-9 1,6-di(4-methoxyphenyl)-1,2,5,6-tetrahydrobis[1,2,4,5]triazaphospholo[4,5-a:4',5'-c]quinoxaline-1,6-disulfide 
• 1361954-68-8 N₃, N₁₀-diphenylbis[1,2,4]triazolo[4,3-a:3',4'-c]quinoxalin-3,10-diamine 
• 20420-56-8 Bis-symm-triazolo<4.3-a,3.4-c>chinoxalin 
• 1372797-36-8 2,3-bis-(benzylidenehydrazino)quinoxaline 
• 1372797-37-9 2,3-bis-(4'-chlorobenzylidenehydrazino)quinoxaline 
• 75380-48-2 2,3-bis(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-ylazo)quinoxaline 

Relevant academic research and scientific papers

Design, Synthesis, and Characterization of Quinoxaline Derivatives as a Potent Antimicrobial Agent

A series of quinoxalinone derivatives were synthesized by the reaction of o-phenylenediamine with oxalic acid to yield 1, 4-dihydro quinoxaline-2, 3-dione (1) and then treated with thionyl chloride to yield 2, 3 dichloro quinoxaline (2). This was further reacted with hydrazine hydrate to produce 2, 3-dihydrazinyl quinoxaline (3). This was finally reacted with substituted aromatic aldehydes to produce 2,3-bis[2-(sustituted benzylidine) hydrazinyl] quinoxalines (4). These quinoxalinone derivatives were characterized by infrared spectroscopy and nuclear magnetic resonance spectroscopy and MASS spectral data. All the synthesized compounds were evaluated for their antimicrobial activity. The results of the antimicrobial study revealed that compounds 4c, 4d, and 4i were active and exhibited better inhibitory activities as compared to standard drug ciprofloxacin. The results were further checked with protein legend interaction by using docking studies, and all the compounds exhibited good docking scores between ?8.72 and ?11.29?kcal/mol against dihydrofolate reductase protein fragment from Staphylococcus aureus (PDB ID-4XE6). Among all compound, 4c has shown maximum docking score and found in agreement to in vitro studies.

Organic electroluminescence material and organic electro-electronic device

The invention provides a compound with a structure as shown as formula I. The invention also provides an application of the compound in an organic electro-electronic device and the organic electro-electronic device. The compound provided by the invention

Synthesis, structural, catecholase, tyrosinase and DFT studies of pyrazoloquinoxaline derivatives

Six functional multidentate ligands: 2,3-bis(3,5-dimethyl-1H-pyrazol-1-yl) quinoxaline, L1, 2,3-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-nitroquinoxaline, L2, 2,3-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylquinoxaline, L3, 2-(3,5-dimethyl-1H-pyrazol-1-yl)-3-hydrazinyl-6-nitroquinoxaline L4, 2-chloro-3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylquinoxaline, L5, 2-chloro-3-(3,5-dimethyl-1H-pyrazol-1-yl) quinoxaline, L6, and a new copper (II) complex, were prepared and evaluated for their catecholase activities at aerobic conditions. We found that, the reaction rate depends on: The nature of the substituents in the quinoxaline ring, counter anion, metal, concentration of ligand and the used solvent. The complex obtained in-situ from reaction of one equivalent of ligand L1 and two equivalents of Cu(CH3COO)2 in methanol showed the highest oxidation rate activity (V?=?33.48?μmol?L?1. min?1). In addition, geometry optimizations of the complexes in order to get better insight into the geometry and the electronic structure and chemical reactivity were carried out by means of DFT calculations.

Synthesis and antimicrobial activity of some novel quinoxalines

2-Hydrazino-3-chloroquinoxaline 2 was prepared and reacted with active methylene compounds, potassium thiocyanate, carbon disulfide, phenylisothiocyanate, acetic acid, ethyl chloroformate, triethyl orthoformate, and Lawessen's reagent (LR) to give a new class of fused quinoxalines 4-16, respectively. Also, 2,3-dihydrazinoquinoxaline 3 was prepared and reacted with carbon disulfide, phenyl isothiocyanate, and triethyl orthoformate to give the corresponding di[1,2,4] triazolo-[4,3-a:3′,4′-c]-quinoxalines 17-19, respectively. Reaction of 3 with LR gave the corresponding di[1,2,4,3] triazophospholo[4,5-a:5′,4′-c]quinoxaline-1,6-dithione (20). It was found that all synthesized compounds exhibit antimicrobial activity and that compound 20 had a broad spectrum of activity. Copyright Taylor & Francis Group, LLC.