73035-16-2

Usage

Uses

Used in Pharmaceutical Industry:
3-ACETYLBENZENESULFONYL CHLORIDE is used as a key intermediate in the synthesis of various pharmaceutical compounds. It serves as a starting material for the preparation of 4-ethylsulfonyl-α-bromoacetophenone, which is then subjected to classical acetamidomalonate addition/decarboxylative hydrolysis to generate the amino acidic moiety. This process is crucial for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
3-ACETYLBENZENESULFONYL CHLORIDE is also utilized as a building block in the synthesis of agrochemicals, such as insecticides, herbicides, and fungicides. Its unique chemical structure allows for the creation of novel compounds with improved efficacy and selectivity in controlling pests and diseases in agriculture.
Used in Specialty Chemicals:
In addition to its applications in pharmaceuticals and agrochemicals, 3-ACETYLBENZENESULFONYL CHLORIDE is employed in the synthesis of specialty chemicals, such as dyes, pigments, and polymers. Its reactivity and functional groups enable the development of innovative materials with unique properties and applications in various industries.

InChI:InChI=1/C8H7ClO3S/c1-6(10)7-3-2-4-8(5-7)13(9,11)12/h2-5H,1H3

Upstream product

• 99-03-6 1-(3-aminophenyl)ethanone 

Downstream Products

• 111711-76-3 1-(3-Acetyl-benzenesulfonyl)-5-ethoxy-pyrrolidin-2-one 
• 74529-64-9 3-(3-Acetyl-benzenesulfonyl)-5,5-diphenyl-oxazolidine-2,4-dione 
• 173158-15-1 3-acetyl-N,N-dimethylbenzenesulfonamide 
• 173158-12-8 N-methyl-3-acetylbenzenesulfonamide 
• 1186422-04-7 3-acetyl-N-[2-(dimethylamino)ethyl]-N-methylbenzenesulfonamide 
• 3814-19-5 1-(3-mercaptophenyl)ethanone 
• 1351823-50-1 4-(5-(6-(3-(ethylthio)phenyl)-2,2'-bipyridin-4-yl)thiophen-2-yl)-N,N-diphenylaniline 
• 1351823-51-2 4-(5-(6-(3-(ethylthio)phenyl)-2,2'-bipyridin-4-yl)thiophen-2-yl)-N,N-bis(4-methoxyphenyl)aniline 
• 1052081-60-3 1-(3-(ethylthio)phenyl)ethanone 
• 1351823-45-4 1-(2-(3-(ethylthio)phenyl)-2-oxoethyl)pyridinium iodide 
• 1351823-47-6 4-(5-bromothiophen-2-yl)-6-(3-(ethylthio)phenyl)-2,2'-bipyridine 
• 1429197-81-8 1-(3-{[(7R,8aS)-7-[(5-cyclopropylpyrazin-2-yl)oxy]hexahydropyrrolo[1,2-a]-pyrazin-2(1H)-yl]sulfonyl}phenyl)ethanone 
• 1353435-00-3 2-hydroxy-4-({[3-(1-hydroxyethyl)phenyl]sulfonyl}amino)benzoic acid 
• 1051162-42-5 4-{[(3-acetylphenyl)sulfonyl]amino}-2-hydroxybenzoic acid 

Relevant academic research and scientific papers

4-PHENYL-N-(PHENYL)THIAZOL-2-AMINE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS

4-phenyl-N-(phenyl)thiazol-2-amine and 4-(pyridin-3-yl)-N-( phenyl) thiazol-2-amine derivatives and the corresponding thiadiazole, thiophene, oxazole, oxadiazole, imidazole and triazole derivatives and related compounds as aryl hydrocarbon receptor (AHR) agonists for the treatment of angiogenesis implicated disorders, such as e.g. retinopathy, psoriasis, rheumatoid arthritis, obesity and cancer, or inflammatory disorders.

LOX ENZYME INHIBITING METHODS AND COMPOSITIONS

This invention relates to compounds, pharmaceutical compositions and their use for treating fibrotic disorders, proliferative disorders, cardiovascular diseases, acute and chronic inflammatory disorders, primary and metastatic cancer, pulmonary conditions, ocular diseases, or neurological and neuropsychiatric conditions. One particular aspect of the inventions relates to inhibitors of the family of lysyl oxidase enzymes and their use as therapeutics for fibrotic disorders.

Dihydrothiazolone compounds containing sulfamide and pharmaceutical compositions and use thereof

The invention provides dihydrothiazolone compounds containing sulfamide, represented by a formula (I), pharmaceutical compositions and use thereof. The compounds can be combined with proteins with bromodomain structural domains so as to adjust a downstream signal channel and exert a special function, and can be used for treating many diseases associated with bromodomain structural domains. The compounds can interfere combination of Brd4 with the bromodomain structural domain and an acetylized histone so as to down-regulate transcription of a cancer gene c-myc and associated target genes thereof, so that the compounds can become effective therapeutic drugs for treating tumors.

Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists

The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.