73038-10-5Relevant academic research and scientific papers
Synthesis of Parabactin Analogues and Formation of Transition Metal Complexes of Parabactin and Related Compounds
Miyasaka, Tadayo,Nagao, Yoshimitsu,Fujita, Eiichi,Sakurai, Hiromu,Ishizu, Kazuhiko
, p. 1542 - 1550 (2007/10/02)
Transition metal complexes of parabactin and its related synthetic spermidine catecholamides which lack the central o-hydroxyphenyloxazoline were studied by the potentiometric titration method, e.s.r. spectroscopy, and fast atom bombardment mass spectrometry (FAB-MS).Direct mass spectral sampling of the parabactin-Fe(III) complex in glycerol solution was first achieved by FAB-MS spectrometry, confirming that the composition of the parabactin-Fe(III) complex is (2-)*2Na(1+) and that the iron(III) ion binds with two catechols and an o-hydroxyphenyl-Δ2-oxazoline moiety in NaOH solution.The e.s.r. g value (4.5) of the parabactin-Fe(III) complex differed from those (4.3) of the 3:1 catechol-Fe(III) complex and other parabactin-related catecholamide-Fe(III) complexes.These results suggest that the structure of the parabactin-Fe(III) complex differs considerably from the regular octahedral structure of the 3:1 catechol-Fe(III) complex and may have a structure similar to the ferrimycobactin P-Fe(III) complex, in which the iron(III) lies exposed in a splayed V-shaped cleft and binds with five oxygens and one nitrogen in a very strained octahedron.
