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2-Amino-5-(p-tolyl)thiazole is a chemical compound with the molecular formula C11H10N2S, belonging to the class of thiazole derivatives. It features a five-membered heterocyclic ring with sulfur and nitrogen atoms, to which a tolyl group is attached. 2-Amino-5-(p-tolyl)thiazole is recognized for its biological activities, such as antimicrobial and antitumor properties, and is being explored for its potential in treating neurodegenerative diseases. The tolyl group's attachment significantly influences the compound's chemical and biological properties, rendering it a valuable building block in organic synthesis.

73040-54-7

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73040-54-7 Usage

Uses

Used in Pharmaceutical Synthesis:
2-Amino-5-(p-tolyl)thiazole is used as a key intermediate in the synthesis of various pharmaceuticals due to its biological activities. Its antimicrobial and antitumor properties make it a promising candidate for developing new drugs targeting a range of diseases.
Used in Agrochemical Synthesis:
In the agrochemical industry, 2-Amino-5-(p-tolyl)thiazole is utilized as a building block for the development of new agrochemicals. Its antimicrobial properties can be harnessed to create effective agents against pests and diseases in agriculture.
Used in Neurodegenerative Disease Treatment Research:
2-Amino-5-(p-tolyl)thiazole is used as a potential therapeutic agent in the research and development of treatments for neurodegenerative diseases. Its biological activities are being studied to understand its potential impact on the progression of such conditions.
Used in Organic Synthesis:
As a valuable building block, 2-Amino-5-(p-tolyl)thiazole is used in organic synthesis to create a variety of chemical compounds. Its unique structure and properties allow for the development of new molecules with specific applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 73040-54-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,0,4 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 73040-54:
(7*7)+(6*3)+(5*0)+(4*4)+(3*0)+(2*5)+(1*4)=97
97 % 10 = 7
So 73040-54-7 is a valid CAS Registry Number.

73040-54-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(4-methylphenyl)-1,3-thiazol-2-amine

1.2 Other means of identification

Product number -
Other names 5-p-tolyl-thiazol-2-ylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:73040-54-7 SDS

73040-54-7Relevant academic research and scientific papers

Facile and efficient preparation of hybrid phenylthiazolyl-1,3,5-triazines and their antidepressant-like effect in mice

Gahtori, Archana,Kumar, Abhay,Kothiyal, Preeti,Gahtori, Prashant

, p. 4987 - 4990 (2015/02/02)

High safety, robust efficacy, and rapid onset of action remain the key challenges for improving antidepressant drug discovery. We report a facile and efficient synthetic strategy to structurally encompass mono-, di-, or tri-substituted derivatives using cyanuric chloride and various substituted phenylthiazole-2-amines. The predicted physicochemical property precisely state their specificity as CNS acting agent and antidepressant-like effect of the most promising compound 10 after oral administration significantly reduced immobility in mice behavior models, especially TST from 63 s. In addition, good safety features of 10 highlight its ability to modulate hallmarks for antidepressant discovery. These insights are useful in generalization and systematization of CRF1antagonist design to develop future biological end points.

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