73053-98-2Relevant academic research and scientific papers
SUBSTITUTED QUINONE INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS AND SYNTHESES AND USES THEREFOR
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, (2008/12/05)
The present invention relates to substituted mdoloqumone compounds of the general formula (A) and (B) and pharmaceutical compositions thereof that are inhibitors of mdoleamme-2,3-dioxygenase (IDO) More specifically, the invention relates to said compounds
Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A
Carr, Gavin,Chung, Marco K. W.,Mauk, A. Grant,Andersen, Raymond J.
, p. 2634 - 2637 (2008/12/22)
Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.
Synthetic studies toward diazonamide A. Preparation of the benzofuranone-indolyloxazole fragment
Wipf, Peter,Yokokawa, Fumiaki
, p. 2223 - 2226 (2007/10/03)
The benzofuranone-indolyloxazole fragment of the polycyclic marine natural product diazonamide A was prepared from tryptamine. The oxazole ring was synthesized from an α keto-indole via cyclodehydration with Ph3P/Cl3CCCl3,
Synthesis of Oxazolylindole Alkaloids from Tryptamine and Tryptophan by Oxidation with 2,3-Dichloro-5,6-dicyanobenzoquinone
Yoshioka, Tadao,Mohri, Kunihiko,Oikawa, Yuji,Yonemitsu, Osamu
, p. 2252 - 2281 (2007/10/02)
When N-acyl derivatives of tryptamine and L-tryptophan methyl ester were treated with DDQ (2 equiv) in tetrahydrofuran or other anhydrous solvents, four consecutive reactions, dehydrogenation, nucleophilic cyclization, another dehydrogenation, and isomeri
