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(S)-N-(1-phenylethyl)pyrazine-2-carboxamide is a chiral organic compound with the molecular formula C15H14N2O. It is a derivative of pyrazine-2-carboxamide, featuring a phenylethyl group attached to the nitrogen atom. (S)-N-(1-phenylethyl)pyrazine-2-carboxamide is known for its potential applications in pharmaceuticals and as a building block in the synthesis of various biologically active molecules. Its chirality arises from the presence of a carbon atom (the one bonded to the phenyl group) that is attached to four different groups, giving it a non-superimposable mirror image, known as an enantiomer. This specific enantiomer, the (S)-isomer, is of interest due to its potential biological activity, which can differ significantly from that of its (R)-counterpart. The compound's structure and properties make it a valuable candidate for further research in drug development and other chemical applications.

73058-36-3

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73058-36-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 73058-36-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,0,5 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 73058-36:
(7*7)+(6*3)+(5*0)+(4*5)+(3*8)+(2*3)+(1*6)=123
123 % 10 = 3
So 73058-36-3 is a valid CAS Registry Number.

73058-36-3Downstream Products

73058-36-3Relevant academic research and scientific papers

Carboxyesterase polypeptides for amide coupling

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Page/Page column 63-64; 73-82, (2021/05/28)

The present invention provides engineered carboxyesterase enzymes having improved properties as compared to a naturally occurring wild-type carboxyesterase enzymes, as well as polynucleotides encoding the engineered carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes in amidation reactions.

Preparation of pyrazine carboxamides: A reaction involving N-heterocyclic carbene (NHC) intermediates

Naredla, Rajasekhar Reddy,Dash, Barada P.,Klumpp, Douglas A.

supporting information, p. 4806 - 4809 (2013/10/08)

In the reactions of 2,3-pyrazinedicarboxylic anhydride with amines and anilines, pyrazine carboxamides are formed in good to excellent yields. A mechanism is proposed involving ring opening of the anhydride and decarboxylation of the heterocyclic ring. Based on other similar heterocyclic decarboxylations, this suggests the involvement of an N-heterocyclic carbene intermediate leading to the product.

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