73069-86-0Relevant academic research and scientific papers
REACTION OF ORGANIC CARBONATES WITH AMINES I. REACTION OF ALKYL PHENYL CARBONATES WITH PRIMARY ALIPHATIC AMINES
Mikheev, V. V.,Svetlakov, N. V.,Garipov, R. M.
, p. 215 - 220 (2007/10/02)
The reaction of alkyl phenyl carbonates with primary aliphatic amines, leading to the formation of N-alkylurethanes, was investigated.The reaction has overall third order, which is explained by the catalytic action of the amine.The effect of the structure of the alkyl radical and the character of the substituent in the phenyl group of the alkyl phenyl carbonates and also the effect of the polarity of the solvent on the rate of the transformation were investigated.The reaction obeys the Hammett equation.
Reactions of Primary and Secondary Amines with Fluoronitrene Generated from Isopropyl N,N-Difluorocarbamate
Klopotek, David L.,Hobrock, Brice G.,Kovacic, Peter,Jones, Martin B.
, p. 1665 - 1667 (2007/10/02)
Isopropyl N,N-difluorocarbamate deaminates primary amines, RNH2, affording RH, N2, RNHCO2-i-C3H7, and RNH2*HF.With secondary amines, dibenzylamine gives bibenzyl, whereas pyrrolidine yields a ring-expansion product, 2,3,4,5-tetrahydropyridazine.The reactions are consistent with the generation of fluoronitrene and subsequent production of the intermediates RN=NH from RNH2 and R2N=N from R2NH.The advantages of using isopropyl N,N-difluorocarbamate as a source of fluoronitrene are discussed.
