73082-81-2Relevant academic research and scientific papers
KINETIC RELATIONSHIPS OF THE REACTION OF 1,3-DIARYL-1-PROPYN-3-ONES WITH MORPHOLINE AND BUTYLAMINE IN POLAR APROTIC SOLVENTS
Korshunov, S. P.,Slyusareva, O. M.,Korzhova, N. V.,Kazantseva, V. M.
, p. 815 - 819 (2007/10/02)
The kinetics of the reaction of substituted 1,3-diphenyl-1-propyn-3-ones with butylamine and morpholine in acetonitrile and DMFA were studied by a polarographic method in the range of 294-323 deg K with the amines at concentrations (0.05-0.1 mol) securing nondependance of the second-order rate constants on the concentration of the amine.The reactions in acetonitrile and DMFA are characterized by lower ΔH(activ.) values and more negative ΔS(activ.) values than the reactions in alcohol.This is due to the larger degree of separation of the charges and to the solvationstate in the aprotic solvents.It is confirmed by data on the effect of the substituents in the substituted ketones on the rate of their reaction with the amines.
