73089-93-7

Basic information

• Product Name: 1-(2-Hydroxyethyl)cyclopentanol
• Synonyms: 1-(2-Hydroxyethyl)cyclopentanol;1-Hydroxycyclopentaneethanol;1-(2-Hydroxyethyl)cyclopentanol - H6282;1-(2-hydroxyethyl)cyclopentan-1-ol
• CAS NO: 73089-93-7
• Molecular Formula: C₇H₁₄O₂
• Molecular Weight: 130.18486
• Mol File: 73089-93-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 256℃
• Flash Point: 123℃
• Appearance: /
• Density: 1.092
• Refractive Index: 1.4815
• PKA: 14.90±0.20(Predicted)
• CAS DataBase Reference: 1-(2-Hydroxyethyl)cyclopentanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Hydroxyethyl)cyclopentanol(73089-93-7)
• EPA Substance Registry System: 1-(2-Hydroxyethyl)cyclopentanol(73089-93-7)

Safety Data

• Hazardous Substances Data: 73089-93-7(Hazardous Substances Data)

Usage

General Description

1-(2-Hydroxyethyl)cyclopentanol, also known as 1-cyclopentanol-1-ethyl-2-ol, is a chemical compound with the molecular formula C8H16O2. It is a colorless liquid with a mild odor, and it is commonly used as a solvent and intermediate in the synthesis of pharmaceuticals, fragrances, and other chemicals. 1-(2-Hydroxyethyl)cyclopentanol is a derivative of cyclopentanol, which is a five-membered cyclic alcohol. The presence of a hydroxyl (-OH) group and an ethyl group attached to the cyclopentane ring gives this compound its unique properties and versatility in various applications. Its structure and properties make it suitable for use in industries such as pharmaceuticals, cosmetics, and flavors, where it can be utilized as a building block for the synthesis of other compounds. Additionally, it is important to handle this chemical with caution, as prolonged or excessive exposure to it may cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 13278-09-6 tert-butyl 2-(1-hydroxycyclopentyl)acetate 
• 120-92-3 cyclopentanone 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 110-52-1 1,4-dibromo-butane 
• 57-57-8 β-Propiolactone 
• 190381-00-1 1-[2'-(allyldimethylsilyl)ethyl]cyclopentan-1-ol 
• 3197-76-0 ethyl 2-(1-hydroxycyclopentyl)acetate 
• 23708-47-6 1,4-bis(bromomagnesium)butane 
• 7499-04-9 2-(1-hydroxycyclopentyl)acetic acid 

Downstream Products

• 3197-73-7 2-(cyclopent-1-en-1-yl)ethanol 
• 120-92-3 cyclopentanone 
• 1140918-74-6 N-{(3E)-5-tert-butyl-1-methyl-2-[(2R)-tetrahydrofuran-2-ylmethyl]-1,2-dihydro-3H-pyrazol-3-ylidene}-2-[2-(1-hydroxycyclopentyl)ethoxy]-5-(trifluoromethyl)benzamide 
• 1369331-34-9 C₂₁H₂₅ClO₂S 
• 1369331-43-0 C₁₄H₁₈O 
• 114694-26-7 (1R,3aS,7aR)-1-[(R)-3-Benzenesulfonyl-1-methyl-4-(1-triethylsilanyloxy-cyclopentyl)-butyl]-4-[2-[(3S,5R)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-indene 
• 114694-28-9 (1R,3aS,7aR)-4-[2-[(3S,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-eth-(E)-ylidene]-7a-methyl-1-[(R)-1-methyl-4-(1-triethylsilanyloxy-cyclopentyl)-butyl]-octahydro-indene 
• 114694-10-9 26,27-trimethylene-1,25-dihydroxyvitamin D₃ 
• 114694-25-6 1-<2-(phenylsulfonyl)ethyl>-1-<(triethylsilyl)oxy>cyclopentane 
• 114694-24-5 1-(2-Benzenesulfonyl-ethyl)-cyclopentanol 
• 114694-23-4 1-(2-Phenylsulfanyl-ethyl)-cyclopentanol 
• 114694-22-3 2-(1-hydroxycyclopentyl)ethyl 4-methylbenzenesulfonate 

Relevant articles and documents

Synthesis and Biological Activity of 2,22-Dimethylene Analogues of 19-Norcalcitriol and Related Compounds

Continuing our search for Vitamin D analogues, we explored the modification of the steroidal side chain and inserted a methylene moiety in position C-22 together with either lengthening the side chain or introducing a ring at the terminal end. Our conform

Synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols or 3-amino alcohols using iodobenzene dichloride and sodium azide

A general and efficient method for the synthesis of oxazolidin-2-ones and imidazolidin-2-ones directly from 1,3-diols and 3-amino alcohols has been developed using the same reagent combination of iodobenzene dichloride (PhICl2) and sodium azide (NaN3).

A new approach to the synthesis of 1-oxaspiro[4.n]alkanes and tetrahydrofurans by the 1,5-CH insertion reaction of magnesium carbenoids

1-Alkoxy-1-[2-chloro-2-(p-tolylsulfinyl)ethyl]cycloalkanes were prepared from various cyclic ketones in good overall yields. Treatment of these cycloalkanes bearing a sulfinyl group with i-PrMgCl resulted in the formation of 1-oxaspiro[4.n]alkanes in high to quantitative yields via the 1,5-CH insertion reaction of generated magnesium carbenoid intermediates. When this procedure was commenced with acyclic ketones, multi-substituted tetrahydrofurans were obtained in up to a 96% yield. This procedure provides a new and good way for the synthesis of 1-oxaspiro[4.n]alkanes and tetrahydrofurans with the formation of a carbon-carbon bond between a carbenoid carbon and a non-activated carbon in high yields. The oxygen atom in the magnesium carbenoid intermediates was proved to act very important roles in the 1,5-CH insertion reaction.