73094-25-4Relevant academic research and scientific papers
Simple, inexpensive, and facile l-prolinamide used as a recyclable organocatalyst for highly efficient large-scale asymmetric direct aldol reactions
Xu, Jiangwei,Fu, Xiangkai,Wu, Chuanlong,Hu, Xiaoyan
, p. 840 - 850 (2011/08/21)
In order to discover a simple, inexpensive, and efficient route to obtain highly enantiomerically enriched anti-aldol products for applications in industry, a series of prolinamides 1-5 with different carbocyclic rings have been synthesized from achiral c
Proline imidazolidinones and enamines in Hajos-Wiechert and Wieland-Miescher ketone synthesis
de Arriba, ángel L. Fuentes,Simón, Luis,Raposo, César,Alcázar, Victoria,Morán, Joaquín R.
experimental part, p. 4841 - 4845 (2009/10/02)
Readily available aromatic prolinamides obtained from the acid chloride of proline hydrochloride and anilines induce large enantiomeric excesses in intramolecular aldol condensations. Imidazolidinones derived from the reaction of the catalyst and enamines
Synthesis and catalytic activities of (S)-1-formylpyrrolidine-2-carboxylic acid derivatives for the enantioselective reductions of both a ketone and a ketimine
Chen, Zhenfei,Zhang, Anjiang,Zhang, Lixue,Zhang, Jing,Lei, Xinxiang
experimental part, p. 266 - 269 (2009/04/10)
A series of (S)-1-formylpyrrolidine-2-carboxylic acid derivatives (6a-t) have been synthesised and examined as chiral organocatalysts in the asymmetric reduction of both ketone 2 and ketimine 3. These organic activators afforded good to moderate enantiose
