731-98-6 Usage
General Description
The chemical compound "(2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(fluoromethyl)oxolane-3,4-diol" is a nucleoside analog that consists of a fluorinated sugar and the nucleobase adenine. It has potential antiviral and antitumor properties due to its ability to inhibit viral and cellular DNA and RNA polymerases. (2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(fluoromethyl)oxolane-3,4-diol may be used in the development of new pharmaceuticals for the treatment of viral infections and cancer. Its unique structure and potential biological activity make it an interesting target for further research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 731-98-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,3 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 731-98:
(5*7)+(4*3)+(3*1)+(2*9)+(1*8)=76
76 % 10 = 6
So 731-98-6 is a valid CAS Registry Number.
731-98-6Relevant articles and documents
Fluorinase-coupled base swaps: Synthesis of [18F]-5′- deoxy-5′-fluorouridines
Winkler, Margit,Domarkas, Juozas,Schweiger, Lutz F.,O'Hagan, David
, p. 10141 - 10143 (2008)
(Chemical Equation Presented) Making F-ases: One-pot fluorination/base-swap biotransformations were developed by coupling the fluorinase enzyme to nucleoside phosphorylases to generate 5′-deoxy-5′-fluoronucleosides (FDAs). These biotransformations are amenable to radiolabeling syntheses starting from [18F]fluoride ion, as exemplified by the synthesis of [18F]-5′-deoxy-5′-fluorouridines (see scheme), and demonstrate a new application of fluorinase as a catalyst for 18F-C bond formation.