731018-45-4Relevant articles and documents
Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators
Heuser, Stefan,Barrett, David G.,Berg, Martina,Bonnier, Benjamin,Kahl, Astrid,De La Puente, Maria Luz,Oram, Niall,Riedl, Rainer,Roettig, Ulrike,Gil, Gema Sanz,Seger, Erich,Steggles, David J.,Wanner, Jutta,Weichert, Andreas G.
, p. 2675 - 2678 (2007/10/03)
A synthetic route towards cyclopropylic compounds, which act as glucokinase activators is described herein. The present synthesis gives easy and rapid access to a wide variety of either sulfones or sulfonamides starting from readily available late-stage intermediates.
SUBSTITUTED ARYLCYCLOPROPYLACETAMIDES AS GLUCOKINASE ACTIVATORS
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Page 85, (2008/06/13)
According to the present invention there is provided a compounds of formula (I): and pharmaceutically acceptable salts thereof.