73105-48-3

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
1-Methyl-5-nitro-1H-indazol-3-ylaMine is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and functional groups make it a valuable building block for the development of new drugs and agrochemicals with improved efficacy and selectivity.
Used in Medicinal Chemistry Research:
1-Methyl-5-nitro-1H-indazol-3-ylaMine is used as a research compound in medicinal chemistry. Its potential pharmacological properties, such as its ability to modulate biological targets and pathways, make it a promising candidate for the discovery of new therapeutic agents.
Used in Organic Synthesis:
1-Methyl-5-nitro-1H-indazol-3-ylaMine is used as a building block in organic synthesis. Its versatile structure and functional groups allow for the development of novel organic compounds with a wide range of applications, including materials science, catalysis, and chemical biology.

Upstream product

• 41339-17-7 5-nitro-1H-indazol-3-amine 
• 74-88-4 methyl iodide 
• 16588-02-6 4-chloro-3-cyanonitrobenzene 
• 60-34-4 methylhydrazine 
• 5228-49-9 1-methyl-5-nitro-1H-indazole 
• 74209-24-8 3-chloro-1-methyl-5-nitro-1H-indazole 
• 60160-68-1 2-cyano-4-nitrophenylhydrazine 
• 17417-09-3 2-fluoro-5-nitrobenzonitrile 

Downstream Products

• 5228-49-9 1-methyl-5-nitro-1H-indazole 

Relevant academic research and scientific papers

A method for the regioselective synthesis of 1-alkyl-1H-indazoles

A method for the regioselective synthesis of 3-unsubstituted 1-alkyl-1H-indazoles, starting with 2-halobenzonitriles and N-alkylhydrazines, is described. The two-step reaction pathway proceeds through the intermediacy of 1-alkyl-3-amino-1H-indazoles follo

SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS

The present invention provides compounds of Formula (I): or stereoisomers, pharmaceutically acceptable salts thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of factor XIa and/or plasma kallikrein which may be used as medicaments.

DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.

PHOTOCHIMIE D'HETEROCYCLES AZOTES-VI. SYNTHESE PAR VOIE PHOTOCHIMIQUE D'AMINO ET D'ALKOXY INDAZOLES

The preparation of different aminoindazoles by nucleophilic aromatic photosubstitution of nitroindazoles by amines is described.In this manner, the amino, methylamino, dimethylamino and diethylamino substituents are introduced in 3, 4, 5 or 7-position.The irradiation in the presence of ethanol gives ethoxyindazoles in only four cases.Two demethylation reactions have been observed: the first one concerns the formation of methylamino derivatives starting from dimethylamine; the second one, the formation of N(H)1-indazoles by irradiation in presence of diethylamine.