7311-84-4

Upstream product

• 15091-32-4 3,4-dibromo-tetrahydro-thiophene 
• 77-79-2 3-Sulfolene 

Downstream Products

• 53336-42-8 3-bromo-2,3-dihydro-thiophene-1,1-dioxide 
• 69451-79-2 3-p-toluenesulfonyl-3-sulfolene 
• 61322-63-2 4-benzylamino-2-thiolene 1,1-dioxide 
• 111916-56-4 2-methyl-3β-phenyl-2,3α,3aβ,6aβ-tetrahydrothieno<2,3-d>isoxazole-4,4-dioxide 
• 111916-62-2 2,6-dimethyl-3β,5α-diphenyl-2,3α,3aβ,4aα,5β,6,7aα,7bβ-octahydrothieno<2,3-d:5,4-d'>diisoxazole-4,4-dioxide 
• 108919-91-1 2,5-dihydro-3-(phenylsulphonyl)thiophene 1,1-dioxide 

Relevant academic research and scientific papers

Synthesis of a stable 2-tributylstannyl-1,3-butadiene precursor

2-Tributylstannyl-1,3-butadiene (1) is prepared in 66% yield by retrochelotropic reaction of the corresponding sulfolene 3.

1,3-dibenzyl-4-halohexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one intermediates

Novel synthetic routes to (3aα,6aα)-1,3-dibenzyl hexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one 5,5-dioxide, a known intermediate in the synthesis of biotin are provided. A novel synthetic route from this intermediate to biotin is also disclosed.