7312-17-6Relevant academic research and scientific papers
Trace amount Cu (ppm)-catalyzed intramolecular cyclization of 2-(gem-dibromovinyl)phenols(thiophenols) to 2-bromobenzofurans(thiophenes)
Ji, Yong,Li, Pinhua,Zhang, Xiuli,Wang, Lei
supporting information, p. 4095 - 4101 (2013/07/05)
An intramolecular cyclization of 2-(gem-dibromovinyl)phenols(thiophenols) to give 2-bromobenzofurans(thiophenes) in the presence of a trace amount of Cu (0.0064 mol%, 25 ppm) has been developed. The reaction provides the desired products in excellent yields under fluoride-free and mild reaction conditions and with a TON (turnover number) of up to 1.5 × 104. The Royal Society of Chemistry 2013.
A highly efficient TBAF-promoted intramolecular cyclization of gem-dibromoolefins for the synthesis of 2-bromobenzofurans(thiophenes)
Chen, Wei,Zhang, Yicheng,Zhang, Lei,Wang, Min,Wang, Lei
supporting information; experimental part, p. 10476 - 10478 (2011/10/31)
A highly efficient tetra-(n-butyl)ammonium fluoride (TBAF)-promoted intramolecular cyclization of gem-dibromoolefins has been developed for the synthesis of 2-bromobenzofused heterocycles. The reaction provides a convenient approach to 2-bromobenzofurans(
Intramolecular cross-coupling of gem-dibromoolefins: A mild approach to 2-bromo benzofused heterocycles
Newman, Stephen G.,Aureggi, Valentina,Bryan, Christopher S.,Lautens, Mark
supporting information; experimental part, p. 5236 - 5238 (2010/01/31)
Highly useful halogenated benzofurans and benzothiophenes are prepared from readily available gem-dibromoolefins using a mild, ligand-free copper catalyzed cross-coupling procedure.
