73123-52-1

Usage

Uses

Used in Pharmaceutical Industry:
4-cyclohexyl-1H-Pyrazole is used as a key intermediate in the synthesis of new pharmaceuticals for its potential to contribute to the development of innovative drugs with enhanced therapeutic properties.
Used in Agrochemical Industry:
4-cyclohexyl-1H-Pyrazole is utilized as a building block in the creation of agrochemicals, specifically for its potential to improve the effectiveness of pesticides and other agricultural chemicals in protecting crops.
Used in Material Science:
4-cyclohexyl-1H-Pyrazole is employed in the development of new materials, leveraging its chemical properties to enhance material performance in various applications.
Used in Antifungal Applications:
4-cyclohexyl-1H-Pyrazole is used as an antifungal agent, capitalizing on its biological activity to combat fungal infections and protect both human health and agricultural products from fungal decay.
Used in Antimicrobial Applications:
4-cyclohexyl-1H-Pyrazole is applied as an antimicrobial agent, harnessing its ability to inhibit the growth of microorganisms, which is beneficial in various medical and industrial settings to prevent contamination and infection.

Upstream product

• 51007-75-1 Cyclohexylmalonaldehyd 
• 73123-63-4 1-Cyclohexyl-2-ethoxyethylen 
• 51007-71-7 2-Cyclohexyl-3-(dimethylamino)-2-propenal 

Relevant academic research and scientific papers

Synthesis of the silver(I) complex of CH2[CH(pz 4Et)2]2 containing the unprecedented [Ag(NO3)4]3- anion: A general method for the preparation of 4-(alkyl)pyrazoles

A general two-step method for the syntheses of 4-(alkyl)pyrazoles has been developed. The first step involves the reaction between organyl diethylacetals and the Vilsmeier reagent to give a mixture of ethoxy-and dimethylamino- acroleins. This mixture reacts directly with hydrazine monohydrogenchloride to yield the desired (4-substituted)pyrazoles. The 4-(phenyl)pyrazole derivative exhibited a markedly lower solubility in common organic solvents. In the solid state structure the phenyl and pyrazolyl groups are nearly coplanar and extensive intermolecular CH-π interactions organize the molecules in two-dimensional sheets that are held in a three dimensional arrangement by NH...N hydrogen bonds. Tetrakis[(4-ethyl)pyrazolyl]propane, CH 2[CH(pz4Et)2]2, was prepared by a transamination reaction and reacts with Ag(NO3) to yield a compound with a 4:3 metal:ligand mole ratio that when crystallized by diffusion of Et2O into an acetone solution produced [Ag2{μ-CH 2[CH(pz4Et)2]2}2] 3[Ag(NO3)4]2 (1). This complex contains dimeric units in which two silver cations are sandwiched between two CH2[CH(pz4Et)]2 ligands and the counterion is the unprecedented tetra(nitrato)argentate anion. ESI mass spectral data support the existence of both the cationic dimeric units and the [Ag(NO 3)4]- anion in solution.

Syntheses with Aliphatic Dialdehydes, XXXVIII. - Synthesis and Properties of Cycloalkylmalonaldehydes

Vilsmeier formylation of cycloalkyl-substituted enol ethers (7,14a - c,23) yields the cycloalkylmalonaldehydes 1 - 5 for the first time.In solution 1 - 5 exist in the (E)-s-(E) enol form as vinylogous carboxylic acids.The reaction of 1 - 5 with suitable electrophiles and nucleophiles leads to cycloalkyl-substituted open-chain (29,30), carbocyclic (31) as well as heterocyclic compounds (32-40) with peculiar properties due to the presence of the lipophilic cycloalkyl group.