73157-43-4Relevant academic research and scientific papers
Extending the Salinilactone Family
Schlawis, Christian,Harig, Tim,Ehlers, Stephanie,Guillen-Matus, Dulce G.,Creamer, Kaitlin E.,Jensen, Paul R.,Schulz, Stefan
, p. 1629 - 1632 (2020/03/13)
Five new members of the salinilactone family, salinilactones D–H, are reported. These bicyclic lactones are produced by Salinispora bacteria and display extended or shortened alkyl side chains relative to the recently reported salinilactones A–C. They were identified by GC/MS, gas chromatographic retention index, and comparison with synthetic samples. We further investigated the occurrence of salinilactones across six newly proposed Salinispora species to gain insight into how compound production varies among taxa. The growth-inhibiting effect of this compound family on multiple biological systems including non-Salinispora actinomycetes was analyzed. Additionally, we found strong evidence for significant cytotoxicity of the title compounds.
Process for the production of phenylmalonic acid mono-esters
-
, (2008/06/13)
Sodium salts of phenylmalonic acid mono-esters are produced by reacting a phenylacetic acid ester with carbon dioxide in the presence of a sodium substituted compound, which is prepared by substituting a sodium atom for a hydrogen atom of an organic compound selected from a group consisting of acetylene, cumene, triphenylmethane, methyl-methylthiomethyl-sulfoxide and dimethyl-sulfoxide, at a temperature in a range of -20° C. to -40° C.
