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73167-03-0

Icosapent sodium, also known as cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt, is a pharmaceutical compound derived from fish oil. It is a type of omega-3 fatty acid that has various health benefits and is used for the treatment and prevention of cardiovascular diseases.
Used in Pharmaceutical Industry:
Icosapent sodium is used as a pharmaceutical agent for reducing thromboxane A2 production and platelet aggregation. It helps in preventing arteriosclerosis and improving cardiovascular health.
Used in Research and Development:
Icosapent sodium is used as a research compound for studying its effect on the pathology of lupus in drug-induced and spontaneous mouse models. It helps in understanding the underlying mechanisms of lupus and developing potential therapeutic interventions.
Used in Pre-treatment of Mouse Alveolar Macrophages:
Icosapent sodium is used as a pre-treatment agent for mouse alveolar macrophages to study the effect and relationship between amiodarone and eicosapentaenoic acid (EPA) concerning cytokine release. This helps in understanding the interaction between these two compounds and their impact on immune responses.
Used in Pharmacological Correction with EPA Supplementation:
Icosapent sodium is used for pharmacological correction with EPA supplementation to examine if it might restore autophagic flux and reduce renal lipotoxicity in mice. This helps in understanding the potential therapeutic effects of Icosapent sodium in treating kidney diseases and improving overall health.

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  • 73167-03-0 Structure

  • Basic information

    1. Product Name: EPA
    2. Synonyms: 5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID;5,8,11,14,17-EICOSAPENTAENOIC ACID;5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID;ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID;ALL CIS 5-8-11-14-17 EPA;ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID;C20:5 (ALL CIS-5,8,11,14,17) ACID;C20:5 OMEGA-3
    3. CAS NO:73167-03-0
    4. Molecular Formula: C20H29O2.Na
    5. Molecular Weight: 324.44
    6. EINECS: N/A
    7. Product Categories: Lipoxygenase (5-)Unsaturated fatty acids and derivatives;LipoxygenaseEnzyme Inhibitors by Enzyme;Omega 3 fatty acids and derivativesBiochemicals Found in Plants;Arachidonic Acid Cascade;Enzyme Inhibitors;L to;Lipids;Polyunsaturated
    8. Mol File: 73167-03-0.mol

  • Chemical Properties

    1. Melting Point: −54-−53 °C(lit.)
    2. Boiling Point: 439.3°C at 760 mmHg
    3. Flash Point: 336°C
    4. Appearance: white/waxy solid
    5. Density: 0.943 g/mL at 25 °C(lit.)
    6. Vapor Pressure: 6.04E-09mmHg at 25°C
    7. Refractive Index: n20/D 1.4977(lit.)
    8. Storage Temp.: −20°C
    9. Solubility: N/A
    10. CAS DataBase Reference: EPA(CAS DataBase Reference)
    11. NIST Chemistry Reference: EPA(73167-03-0)
    12. EPA Substance Registry System: EPA(73167-03-0)

  • Safety Data

    1. Hazard Codes: C
    2. Statements: 34
    3. Safety Statements: 26-36/37/39-45
    4. RIDADR: UN 3265 8/PG 3
    5. WGK Germany: 3
    6. RTECS:
    7. F: 8-10-23
    8. HazardClass: N/A
    9. PackingGroup: N/A
    10. Hazardous Substances Data: 73167-03-0(Hazardous Substances Data)

73167-03-0 Usage

Biochem/physiol Actions

Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis.

Check Digit Verification of cas no

The CAS Registry Mumber 73167-03-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,1,6 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 73167-03:
(7*7)+(6*3)+(5*1)+(4*6)+(3*7)+(2*0)+(1*3)=120
120 % 10 = 0
So 73167-03-0 is a valid CAS Registry Number.
InChI:InChI=1/C20H30O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22;/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22);/b4-3-,7-6-,10-9-,13-12-,16-15-;

73167-03-0 Well-known Company Product Price

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  • Sigma

  • (E6627)  cis-5,8,11,14,17-Eicosapentaenoicacidsodiumsalt  ≥99% (capillary GC)

  • 73167-03-0

  • E6627-5MG

  • 512.46CNY

  • Detail

  • Sigma

  • (E6627)  cis-5,8,11,14,17-Eicosapentaenoicacidsodiumsalt  ≥99% (capillary GC)

  • 73167-03-0

  • E6627-25MG

  • 1,798.29CNY

  • Detail

73167-03-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name EPA

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:73167-03-0 SDS

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