73170-51-1Relevant academic research and scientific papers
V8 PROTEINASE-CATALYZED PEPTIDE SYNTHESIS IN HYDROPHILIC ORGANIC SOLVENTS WITH LOW WATER CONTENT
Cerovsky, Vaclav
, p. 3421 - 3424 (2007/10/02)
Free Staphylococcus aureus V8 proteinase was applied to coupling reactions of Z-Glu-OMe, Z-Glu-OBzl, Z-Ala-Glu-OMe, and Z-Ala-Ala-Glu-OMe with various amino acid amides and peptides in acetonitrile containing 5 vol. percent of water.No synthesis of Z-Asp-Leu-NH2 was achieved under the same conditions.The synthesis of Z-Glu-Leu-NH2 proceeded analogously also in 2-propanol or tert-butanol.
