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• 3156-37-4 (E)-1-bromo-4-(2-nitrovinyl)benzene 

Relevant academic research and scientific papers

Calix[6]arene-based Br?nsted acids for molecular recognition and catalysis

We report the synthesis of a versatile trifluoromethylsulfonamide calix[6]arene derivative with Br?nsted acid features which can influence both molecular recognition and catalytic application. Indeed, in low polarity media, the trifluoromethyl-containing

Trisulfonamide calix[6]arene-catalysed Michael addition to nitroalkenes

We describe the application of a novel family of trisulfonamide (TSA) calix[6]arenes in general acid catalysis. Hydrogen-bonding interactions between acidic TSA and methanol boosted the reactivity of the Michael addition of indoles to nitroalkene derivati

Electrostatically enhanced phosphoric acids and their applications in asymmetric friedel-crafts alkylations

A series of electrostatically enhanced phosphoric acid catalysts were synthesized and studied. These compounds possess two positively charged N-octylpyridinium or triarylphosphonium ion centers at the 3,3′-positions of the (R)-BINOL backbone to enhance re

Design of a Primary-Amide-Functionalized Highly Efficient and Recyclable Hydrogen-Bond-Donating Heterogeneous Catalyst for the Friedel-Crafts Alkylation of Indoles with β-Nitrostyrenes

A primary-amide-functionalized metal organic framework, {[Zn2(2-BQBG)(BDC)2]·10H2O}n (1) (in which 2-BQBG = 2,2′-(butane-1,4-diylbis((quinolin-2-ylmethyl)azanediyl))diacetamide and BDC = 1,4-benzenedicarboxylate

Friedel-Crafts alkylation reaction with fluorinated alcohols as hydrogen-bond donors and solvents

An effective and clean FC alkylation of indoles and electron-rich arenes with β-nitroalkenes in HFIP was reported. The desired products are formed rapidly in excellent yields under mild conditions without the need for any additional catalysts or reagents. Further, this methodology can be applied to one-pot synthesis of biologically active tryptamine derivatives.

Compound and its preparation method and application

The invention provides a compound and a preparation method therefore and application thereof. The compound is a compound shown in a formula I or an enantiomer, a diastereoisomer, raceme, pharmaceutically acceptable salt, a crystalline hydrate or a solvate of the compound, wherein R1 is optionally substituted phenyl, R2 is p-methylphenyl and X is C or N. The compound can be used for treating cancer related diseases. The formula I is shown in the description.

Friedel–Crafts Alkylation of Indoles with Nitroalkenes through Hydrogen-Bond-Donating Metal–Organic Framework

Urea-derived hydrogen-bond-donating (HBD) catalysts are good catalysts for organic transformations. Usually, urea derivatives undergo self-recognition and aggregation during homogeneous catalytic processes. To avoid this, a new approach involving the inco

Water-soluble (salicyladimine)2Cu complex as an efficient and renewable catalyst for Michael addition of indoles to nitroolefins in water

An efficient and environmentally friendly protocol has been demonstrated for water-soluble (salicyladimine)2Cu complex-catalyzed Michael addition of indoles to nitroolefins in water at 30 °C. A variety of substituted indoles and β-nitrostyrenes could be worked well to provide the title products in 81–97% yields. Moreover, the catalyst can be reused directly at least for four times without significantly decreasing activity.

Design and synthesis of squaramide-based MOFs as efficient MOF-supported hydrogen-bonding organocatalysts

Herein, we utilize a new, squaramide-based ligand, combined with a postsynthetic exchange (PSE) synthetic approach to prepare a series of Cu(ii)-squaramide MOFs that are active catalysts for the Friedel-Crafts reaction.

2,6-Bis(amido)benzoic Acid with Internal Hydrogen Bond as Br?nsted Acid Catalyst for Friedel-Crafts Reaction of Indoles

Benzoic acid catalysts bearing two amide groups that increase the Br?nsted acidity of the carboxylic acid moiety by internal hydrogen-bonding interactions were designed as a novel class of carboxylic acid catalysts for the Friedel-Crafts reaction of indol