731843-42-8Relevant articles and documents
Bis-Ketol Nucleoside Triesters as Prodrugs of the Antiviral Nucleoside Triphosphate Analogues of 3′-Deoxythymidine and 3′-Deoxy-2′ ,3′-didehydrothymidine
Calvo, Kim C.,Wang, Xiaohong,Koser, Gerald F.
, p. 637 - 646 (2007/10/03)
Derivatives of 3′-deoxythymidine (ddT) and 3′-deoxy-2′ ,3′-didehydrothymidine (d4T) were prepared in which the 5′-hydroxyl group of the nucleoside was esterified to a bisketol phosphate. The resulting phosphate triesters are postulated to be prodrugs of t