731856-83-0

Upstream product

• 43028-74-6 ethyl 2-amino-5-cyano-4-methyl-3-thiophenecarboxylate 
• 731855-64-4 2-(3,4-dimethoxybenzyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carbonitrile 
• 35161-71-8 methyl(propargyl)amine 
• 1628755-38-3 C₁₇H₁₄ClN₃O₂S 

Relevant academic research and scientific papers

Microwave-assisted synthesis of potent PDE7 inhibitors containing a thienopyrimidin-4-amine scaffold

A series of novel thienopyrimidin-4-amines have been synthesized and evaluated as phosphodiesterase (PDE) inhibitors. A rationale for the observed selectivity against PDE7 has been obtained from molecular modelling studies on the most active compounds. This journal is the Partner Organisations 2014.

4-AMINOTHIENO[2,3-d]PYRIMIDINE-6-CARBONITRILE DERIVATIVES AS PDE7 INHIBITORS

New 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives having the chemical structure of general formula (I), and pharmaceutically acceptable salts thereof are disclosed as well as processes for their preparation and to pharmaceutical compositions c