73217-33-1 Usage
Uses
Used in Medicinal Chemistry:
3-(CHLOROMETHYL)-5-(4-METHYLPHENYL)-1,2,4-OXADIAZOLE is used as a potential antifungal agent for its studied properties in combating fungal infections.
Used in Pharmaceutical Drug Development:
3-(CHLOROMETHYL)-5-(4-METHYLPHENYL)-1,2,4-OXADIAZOLE serves as a building block in the development of new pharmaceutical drugs, leveraging its unique structure and functional groups for medicinal purposes.
Used in Chemical Synthesis:
3-(CHLOROMETHYL)-5-(4-METHYLPHENYL)-1,2,4-OXADIAZOLE is used as a versatile intermediate in chemical synthesis, particularly for creating new compounds with potential applications in various industries.
Safety Consideration:
It is important to handle 3-(CHLOROMETHYL)-5-(4-METHYLPHENYL)-1,2,4-OXADIAZOLE with care due to the reactivity of the chloromethyl group, which can form potentially hazardous byproducts when reacting with other compounds. Proper safety measures should be taken during its use and manipulation.
Check Digit Verification of cas no
The CAS Registry Mumber 73217-33-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,2,1 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 73217-33:
(7*7)+(6*3)+(5*2)+(4*1)+(3*7)+(2*3)+(1*3)=111
111 % 10 = 1
So 73217-33-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H9ClN2O/c1-7-2-4-8(5-3-7)10-12-9(6-11)13-14-10/h2-5H,6H2,1H3
73217-33-1Relevant academic research and scientific papers
ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF
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Page/Page column 62, (2012/01/13)
The present invention relates to alkaloid aminoester derivatives acting as muscarinic receptor antagonists, processes for their preparation, compositions comprising them and therapeutic uses thereof.
The discovery of a selective, high affinity A2B adenosine receptor antagonist for the potential treatment of asthma
Zablocki, Jeff,Kalla, Rao,Perry, Thao,Palle, Venkata,Varkhedkar, Vaibhav,Xiao, Dengming,Piscopio, Anthony,Maa, Tenning,Gimbel, Art,Hao, Jia,Chu, Nancy,Leung, Kwan,Zeng, Dewan
, p. 609 - 612 (2007/10/03)
Adenosine has been suggested to play a role in asthma, possibly via activation of A2B adenosine receptors on mast cells and other pulmonary cells. We describe our initial efforts to discover a xanthine based selective A2B AdoR antagonist that resulted in the discovery of CVT-5440, a high affinity A2B AdoR antagonist with good selectivity (A2B AdoR Ki = 50 nM, selectivity A1 > 200: A2A > 200: A3 > 167).
