73220-39-0

Usage

Uses

Used in Pharmaceutical and Medicinal Chemistry:
6-chloro-3-iodo-4H-chromen-4-one is used as a chemical intermediate for the synthesis of various pharmaceutical and medicinal compounds. Its unique structure and functional groups make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Organic Synthetic Methodologies:
6-chloro-3-iodo-4H-chromen-4-one is used as a key building block in the development of new organic synthetic methodologies. Its reactivity and functional groups can be exploited to create novel synthetic routes and strategies for the preparation of complex organic molecules.
Used in Biological Research:
6-chloro-3-iodo-4H-chromen-4-one may exhibit biological activities, making it a valuable tool for biological research. Its unique structure can be used to probe the interactions between small molecules and biological targets, such as enzymes, receptors, and other proteins.
Used in Chemical Synthesis:
6-chloro-3-iodo-4H-chromen-4-one is used as a versatile synthetic building block in chemical synthesis. Its functional groups can be modified and transformed to generate a wide range of chemical products, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Material Science:
6-chloro-3-iodo-4H-chromen-4-one may have potential applications in material science, such as in the development of new materials with unique properties. Its structure and functional groups can be utilized to create novel materials with potential applications in various industries, including electronics, energy, and environmental protection.

Upstream product

• 73220-32-3 (2E)-1-(5-chloro-2-hydroxyphenyl)-3-(dimethylamino)-2-propen-1-one 
• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 67829-05-4 1-(3-chlorophenyl)-2-hydroxyethanone 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 73220-32-3 C₁₁H₁₂ClNO₂ 

Downstream Products

• 1020839-87-5 2-[4-(4-amino-phenylethynyl)-1-(2-hydroxy-ethyl)-1H-pyrazol-3-yl]-4-chloro-phenol 
• 1020840-26-9 2-[4-(4-amino-phenylethynyl)-1H-pyrazol-3-yl]-4-chloro-phenol 
• 42972-67-8 6-chloro-3-phenyl-4H-chromen-4-one 
• 131168-61-1 6-chloro-3-(p-tolyl)-4H-chromen-4-one 
• 145013-56-5 6-chloro-3-(4-chlorophenyl)-4H-chromen-4-one 
• 130252-74-3 6-chloro-3-(4-methoxyphenyl)-4H-chromene-4-one 
• 1429426-11-8 2-(5-chloro-2-hydroxybenzoyl)-4H-furo[3,2-c]chromen-4-one 

Relevant academic research and scientific papers

Synthesis of multisubstituted 2-aminopyrroles/pyridines via chemoselective michael addition/intramolecular cyclization reaction

A facile and efficient synthetic strategy to construct polysubstituted 2-aminopyrroles/pyridines was developed via chemoselective Michael addition/intramolecular cyclization reaction under very mild conditions. It suggested that the chemoselectivity of the process could be controlled by the leaving ability of the halides.

Synthesis of 3-halochromones with simple KX halogen sources enabled by: In situ halide oxidation

On the basis of a designated in situ oxidation tactic, the synthesis of 3-halochromones has been realized for the first time by using simple KX (X = Br, I) salts as halogen sources. Instead of the free radical process, the control experiments indicate that the reported reactions proceed through a halogenium intermediate. Compared to the known synthetic methods relying on molecular halogen, haloid acid or N-halosuccinimide as the halogen source, the present method is attractive due to its higher atom economy and being more friendly to the operator, thus providing a practical complimentary approach to the preparation of useful halochromone compounds.

Synthesis of Functionalized Chromeno[2,3-b]pyrrol-4(1H)-ones by Silver-Catalyzed Cascade Reactions of Chromones/Thiochromones and Isocyanoacetates

A novel and convenient approach to the synthesis of chromeno[2,3-b]pyrrol-4(1H)-ones has been developed. Furthermore, the method involves a facile silver-catalyzed cascade cyclization reaction including an intramolecular C-O bond formation. The silver sal

Synthesis, antimycobacterial evaluation and pharmacophore modeling of analogues of the natural product formononetin

Abstract The synthesis and antimycobacterial activity of formononetin analogues is hereby reported. Formononetin and its analogue 11E showed 88% and 95% growth inhibition, respectively, against the H37Rv strain of Mycobacterium tuberculosis. Pharmacophore modeling studies indicated that the presence of a hydroxyl group in formononetin and its analogues, is crucial for maintaining activity.