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BDZ-g, also known as benzodiazepine-gamma, and GYKI 47409 are two distinct chemical compounds with potential pharmaceutical applications. BDZ-g is a molecule that has been studied for its potential as a central nervous system depressant, similar to benzodiazepine drugs, and it interacts with gamma-aminobutyric acid (GABA) receptors in the brain, which are involved in the regulation of anxiety and sedation. GYKI 47409 is a selective AMPA receptor antagonist, indicating its potential to modulate the activity of the neurotransmitter glutamate in the brain, making it a candidate for the treatment of conditions involving glutamate dysregulation, such as neurodegenerative diseases or chronic pain. Both chemicals have shown promise in preclinical studies, and further research may reveal their potential as therapeutic agents.

732278-52-3

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732278-52-3 Usage

Uses

Used in Pharmaceutical Industry:
BDZ-g,GYKI 47409, is used as a central nervous system depressant for its interaction with GABA receptors, which helps in the regulation of anxiety and sedation.
Used in Neurodegenerative Disease Treatment:
BDZ-g,GYKI 47409, is used as a selective AMPA receptor antagonist for modulating the activity of the neurotransmitter glutamate in the brain, which could be beneficial in the treatment of neurodegenerative diseases or chronic pain conditions where glutamate dysregulation is implicated.

Check Digit Verification of cas no

The CAS Registry Mumber 732278-52-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,3,2,2,7 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 732278-52:
(8*7)+(7*3)+(6*2)+(5*2)+(4*7)+(3*8)+(2*5)+(1*2)=163
163 % 10 = 3
So 732278-52-3 is a valid CAS Registry Number.

732278-52-3Upstream product

732278-52-3Downstream Products

732278-52-3Relevant academic research and scientific papers

Novel substituted 2,3-benzodiazepine derivatives

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Page/Page column 26, (2010/02/08)

The invention relates to new 2,3-benzodiazepine derivatives of formula (I), isomers and acid addition salts thereof and to pharmaceutical compositions containing the same, as well as to pharmaceutical compositions and methods of using the same suitable fo

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