73271-41-7

Usage

General Description

1-METHYL-3-[(4-METHYLPHENYL)IMINO]-1,3-DIHYDRO-2H-INDOL-2-ONE is a chemical compound with the molecular formula C17H16N2O. It is an indole derivative with a methyl group and a phenylimino group attached to the indole ring. 1-METHYL-3-[(4-METHYLPHENYL)IMINO]-1,3-DIHYDRO-2H-INDOL-2-ONE has potential pharmaceutical applications, particularly in the field of medicinal chemistry and drug discovery. Its unique chemical structure makes it a promising candidate for the development of new drugs targeting various biological processes. Further research and investigation are necessary to fully understand the potential uses and effects of 1-METHYL-3-[(4-METHYLPHENYL)IMINO]-1,3-DIHYDRO-2H-INDOL-2-ONE.

Upstream product

• 2058-74-4 1-methyl-1H-indole-2,3-dione 
• 106-49-0 p-toluidine 
• 1128-44-5 4-methyl-1H-indole-2,3-dione 

Downstream Products

• 79560-78-4 C₁₇H₁₆N₄OS 
• 3893-33-2 benzil monoazine 
• 96859-88-0 C₃₀H₂₄N₂O₂ 
• 1210949-03-3 diisopropyl 3-(p-tolylamino)-1-methyl-2-oxoindolin-3-ylphosphonate 
• 1210948-84-7 diethyl 1-methyl-2-oxo-3-(p-tolylamino)indolin-3-ylphosphonate 
• 1373770-80-9 methyl 1',3-dimethyl-2',4-dioxo-1-(p-tolyl)spiro[azetidine-2,3'-indoline]-3-carboxylate 

Relevant academic research and scientific papers

Some organotellurium(iv) complexes of 1-methyl-3-(p-tolylimino)indolin-2-one schiff base

Six new hexa-coordinated organotellurium(IV) complexes of type RTeCl3 NMeIPT and R2TeCl2 NMeIPT (R = 4-hydroxyphenyl, 4- methoxyphenyl or 3-methy-4-hydroxyphenyl; NMeIPT(L) = Schiff base (1-methyl-3-(p-tolylimino)indolin-2-one) derived from condensation o

Synthesis of Novel Spiro[indol-2,2′-pyrroles] Using Isocyanide-Based Multicomponent Reaction

An efficient and facile method for the synthesis of novel spiro[indole-2,2′-pyrroles] from N-methyl-3-isatin imines, t-butyl isocyanide, and dialkyl acetylenedicarboxylate has been achieved by [3 + 2] cyclo addition reaction. All the products were purifie

A copper-catalyzed one-pot, three-component diastereoselective synthesis of 3-spiroazetidinimine-2-oxindoles and their synthetic transformation into fluorescent conjugated indolones

A facile and efficient copper(I)-catalyzed one-pot, three-component diastereoselective synthesis that provides new 3-spiroazetidinimine-2-oxindoles in excellent yield has been accomplished. The 3-spiroazetidinimine-2-oxindoles underwent a facile ring-open

A Copper-Catalyzed One-Pot, Three-Component Diastereoselective Synthesis of 3-Spiroazetidinimine-2-oxindoles and Their Synthetic Transformation into Fluorescent Conjugated Indolones

A facile and efficient copper(I)-catalyzed one-pot, three-component diastereoselective synthesis that provides new 3-spiroazetidinimine-2-oxindoles in excellent yield has been accomplished. The 3-spiroazetidinimine-2-oxindoles underwent a facile ring-opening reaction of the spiroazetidinimine unit by treatment with KOH/MeOH and p-thiocresol under basic conditions to afford two new classes of fluorescent conjugated indolones. This method has general applications with regard to the imines that are derived from 9-fluorenone, 1,2-diketones, and 1,2,3-triketones. A facile and efficient copper(I)-catalyzed one-pot, three-component diastereoselective synthesis that provides new 3-spiroazetidinimine-2-oxindoles in excellent yield has been accomplished. The ring-opening reaction of the 3-spiroazetidinimine-2-oxindoles has also been described. This method has general applications with regard to the imines of 9-fluorenone, 1,2-diketones, and 1,2,3-triketones.

Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors

The isatin core structure was found to be a novel chemical scaffold in transthyretin (TTR) fibrillogenesis inhibitor design. Among the series of isatin analogues prepared and tested, the nitro compound 1,3-dihydro-3-[(4-nitrophenyl)imino]-2H-indol-2-one (2r) is as potent as triiodophenol, which is one of the most active known TTR inhibitors. The E/Z stereochemistry of these molecules in solution, elucidated by 1H NMR, does not influence their biological activity. The compounds do not bind to the native tetrameric TTR suggesting that their inhibitory action is independent of the protein binding and stabilization.

Reactions of α-diazoketones with indolinone imines: Synthesis of new 1,3,3-triaryl-1′-methylspiro[azetidine-2,3′-indoline]-2′, 4-diones

The paper describes the synthesis of new 1,3,3-triary-1′- methylspiro[azetidine-2,3′-indoline]-2′,4-diones from reaction of the 2-diazo-1,2-diarylethanones with 3-arylimino-1-methyl-2-indolinones. The compounds have been characterized by satisfactory anal

Reactions of 3-Arylimino-2-Indolinones with p-Substituted Phenylthiosemicarbazides

3-Arylimino-2-indolinones (II) have been prepared by the condensation of isatins (I) with anilines.Reactions of II with p-substituted phenylthiosemicarbazides have resulted (in every instance) in the displacement of arylimino groups by the phenylthiosemic