73271-41-7Relevant articles and documents
Some organotellurium(iv) complexes of 1-methyl-3-(p-tolylimino)indolin-2-one schiff base
KUMAR, MANISH,VERMA,GARG, SAPANA
, p. 1236 - 1244 (2021/06/09)
Six new hexa-coordinated organotellurium(IV) complexes of type RTeCl3 NMeIPT and R2TeCl2 NMeIPT (R = 4-hydroxyphenyl, 4- methoxyphenyl or 3-methy-4-hydroxyphenyl; NMeIPT(L) = Schiff base (1-methyl-3-(p-tolylimino)indolin-2-one) derived from condensation o
A copper-catalyzed one-pot, three-component diastereoselective synthesis of 3-spiroazetidinimine-2-oxindoles and their synthetic transformation into fluorescent conjugated indolones
Periyaraja, Somasundharam,Shanmugam, Ponnusamy,Mandal, Asit Baran
, p. 954 - 965 (2014/03/21)
A facile and efficient copper(I)-catalyzed one-pot, three-component diastereoselective synthesis that provides new 3-spiroazetidinimine-2-oxindoles in excellent yield has been accomplished. The 3-spiroazetidinimine-2-oxindoles underwent a facile ring-open
Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors
Gonzalez, Asensio,Quirante, Josefina,Nieto, Joan,Almeida, Maria Rosario,Saraiva, Maria Joao,Planas, Antoni,Arsequell, Gemma,Valencia, Gregorio
supporting information; experimental part, p. 5270 - 5273 (2010/03/24)
The isatin core structure was found to be a novel chemical scaffold in transthyretin (TTR) fibrillogenesis inhibitor design. Among the series of isatin analogues prepared and tested, the nitro compound 1,3-dihydro-3-[(4-nitrophenyl)imino]-2H-indol-2-one (2r) is as potent as triiodophenol, which is one of the most active known TTR inhibitors. The E/Z stereochemistry of these molecules in solution, elucidated by 1H NMR, does not influence their biological activity. The compounds do not bind to the native tetrameric TTR suggesting that their inhibitory action is independent of the protein binding and stabilization.