73282-15-2Relevant academic research and scientific papers
Eosin y photoredox catalyzed net redox neutral reaction for regiospecific annulation to 3-sulfonylindoles: Via anion oxidation of sodium sulfinate salts
Rohokale, Rajendra S.,Tambe, Shrikant D.,Kshirsagar, Umesh A.
, p. 536 - 540 (2018)
An eosin Y photoredox catalyzed net redox neutral process for 3-sulfonylindoles via the anionic oxidation of sodium sulfinate salts and its radical cascade cyclization with 2-alkynyl-azidoarenes was developed with visible light as a mediator. The reaction offers metal and oxidant/reductant free, visible light mediated vicinal sulfonamination of alkynes to 2-aryl/alkyl-3-sulfonylindoles and proceeds via the generation of a sulfur-centered radical through direct oxidation of the sulfinate anion by an excited photocatalyst with a reductive quenching cycle. The mild conditions, use of an organic dye as photo-catalyst, bench stability and easily accessible starting materials make the present approach green and attractive.
Tert-Butyl Hydroperoxide (TBHP)-Initiated Vicinal Sulfonamination of Alkynes: A Radical Annulation toward 3-Sulfonylindoles
Chen, Fei,Meng, Qiang,Han, Shang-Qing,Han, Bing
supporting information, p. 3330 - 3333 (2016/07/26)
A novel, efficient, and facile vicinal sulfonamination of alkynes by the reaction of accessible 2-alkynyl arylazides with sulfinic acids in the presence of tert-butyl hydroperoxide (TBHP) has been developed. This protocol utilizes sulfinic acids as the su
