73302-35-9Relevant academic research and scientific papers
Metal-Free Mild Synthesis of Novel 1′ H -Spiro[Cycloalkyl-1,2′-quinazolin]-4′(3′ H)-ones by an Organocatalytic Cascade Reaction
Ramesh, Rathinam,Kalisamy, Periyathambi,Malecki, Jan Grzegorz,Lalitha, Appaswami
, p. 203 - 208 (2018)
A concise organocatalytic method for the facile synthesis of some novel 1′ H -spiro[cycloalkyl-1,2′-quinazolin]-4′(3′ H)-ones via a one-pot, three-component condensation of isatoic anhydride, aryl or aliphatic amines and a cyclic ketone is described.
Ferric (III) complex supported on superparamagnetic Fe3O4@SiO2 as a reusable Lewis acid catalyst: a new highly efficient protocol for the synthesis of acridinedione and spiroquinazolin-4(3H)-one derivatives
Mohammadi, Hadi,Shaterian, Hamid Reza
, p. 179 - 195 (2019/08/08)
Nano-Fe3O4@SiO2-3,4-dihydroxybenzaldehyde/barbituric acid/phthalhydrazide-FeCl3 (nano-Fe3O4@SiO2-HBP-FeCl3) was prepared and authenticated by usual analytical and spectroscopic techniques. The prepared nano-Fe3O4@SiO2-HBP-FeCl3 was applied to acridinedione and spiroquinazolin-4(3H)-one derivatives under green conditions. In addition, this research offers several advantages such as very easy reaction conditions, simple work-up, excellent yields, high purity of the desired product, short reaction time and one-pot reaction to synthesize Fe3O4@SiO2-HBP-FeCl3. The recycling studies revealed that catalyst could be easily recovered using an external magnet and reused five times without significant loss of its catalytic activity.
