73318-14-6

Basic information

• Product Name: Benzoic acid, 2-amino-3-cyano-4,5-dimethyl-, methyl ester (9CI)
• Synonyms: Benzoic acid, 2-amino-3-cyano-4,5-dimethyl-, methyl ester (9CI)
• CAS NO: 73318-14-6
• Molecular Formula: C₁₁H₁₂N₂O₂
• Molecular Weight: 204.22518
• Product Categories: AMINOACID
• Mol File: 73318-14-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 2-amino-3-cyano-4,5-dimethyl-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-amino-3-cyano-4,5-dimethyl-, methyl ester (9CI)(73318-14-6)
• EPA Substance Registry System: Benzoic acid, 2-amino-3-cyano-4,5-dimethyl-, methyl ester (9CI)(73318-14-6)

Safety Data

• Hazardous Substances Data: 73318-14-6(Hazardous Substances Data)

Upstream product

• 5117-88-4 2-amino-3-cyano-4,5-dimethylfuran 
• 292638-85-8 acrylic acid methyl ester 
• 73318-13-5 Methyl 2-Amino-3-cyano-4,5-dimethyl-5-hydroxy-1,3-cyclohexadiene-1-carboxylate 

Downstream Products

• 186834-07-1 methyl N-(2-bromopropanoyl)-3-cyano-4,5-dimethylanthranilate 
• 86542-76-9 2,6,7-Trimethyl-4-oxo-3-o-tolyl-3,4-dihydro-quinazoline-8-carbonitrile 
• 86549-49-7 methyl 2-acetamido-3-cyano-4,5-dimethylbenzoate 
• 73318-18-0 2-Acetamido-5,6-dimethyl-3-methoxycarbonylbenzoic Acid 

Relevant articles and documents

Synthesis, local anaesthetic and antiarrhythmic activity of methyl N-(2-substituted aminopropanoyl)-3-cyanoanthranilates

A series of methyl N-(2-substituted aminopropanoyl)-3-cyanoanthranilates (4a-i), that are structurally-related to tocainide and lidocaine, was synthesized and was found to be active when evaluated for local anaesthetic activity using the frog-foot withdrawal reflex, the guinea pig wheal derm and the rabbit corneal reflex tests. A selected numbers of the series were preliminarily evaluated for antiarrhythmic activity using CaCl2-induced arrhythmia test. Compounds 4a, 4c and 4f at lower doses completely protected the animals against the induced arrhythmias.